Shanghai Nianxing Industrial Co., Ltd
China
Product Name: HEPPS
Price:
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: HEPPS
Price: ￥378.0/100g ￥118.0/25g ￥2268.0/500g ￥388.0/100g
Purity: 99.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: EPPS
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: EPPS
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: hepps
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

16052-06-5

16052-06-5 structure

16052-06-5 structure

Name: HEPPS
Chemical Name: hepps
CAS Number: 16052-06-5
Molecular Formula: C₉H₂₀N₂O₄S
Molecular Weight: 252.331
Catalog: Research Areas Neurological Disease
Create Date: 2018-04-09 08:00:00
Modify Date: 2024-01-02 12:30:48
HEPPS (EPPS) is a buffering agent with the useful pH range from 7.3 ~ 8.7. HEPPS reduces Aβ-aggregate-induced memory deficits and rescues cognitive deficits in mice. EPPS is orally active and penetrates the blood-brain barrier[1].

Name	hepps
Synonyms	HEPPS 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonic Acid EINECS 240-198-8 MFCD00006160 3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid 3-(4-(2-Hydroxyethyl)piperazin-1-yl)propane-1-sulfonic acid 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic Acid [Good's buffer component 1-Piperazinepropanesulfonic acid, 4-(2-hydroxyethyl)- 3-[4-(2-Hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid EPPS 4-Hydroxyerhylpiperazine-1-propanesulfonic acid

Description	HEPPS (EPPS) is a buffering agent with the useful pH range from 7.3 ~ 8.7. HEPPS reduces Aβ-aggregate-induced memory deficits and rescues cognitive deficits in mice. EPPS is orally active and penetrates the blood-brain barrier[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Kim HY, et al. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nat Commun. 2015 Dec 8;6:8997.

Density	1.3±0.1 g/cm3
Melting Point	237-239 °C(lit.)
Molecular Formula	C₉H₂₀N₂O₄S
Molecular Weight	252.331
Exact Mass	252.114380
PSA	89.46000
LogP	-2.46
Index of Refraction	1.537
Storage condition	Store at RT.
Water Solubility	H2O: 1 M at 20 °C, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM2649130

CHEMICAL NAME :: 1-Piperazinepropanesulfonic acid, 4-(2-hydroxyethyl)-

CAS REGISTRY NUMBER :: 16052-06-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H20-N2-O4-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >316 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TM2649130
HS Code	29335995

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%