80-63-7
80-63-7 structure
- Name: Methyl alpha-chloroacrylate
- Chemical Name: 2-Propenoic acid, 2-chloro-, methyl ester
- CAS Number: 80-63-7
- Molecular Formula: C4H5ClO2
- Molecular Weight: 120.53400
- Catalog: Chemical reagent Organic reagent Ester Acid ester compound
- Create Date: 2018-09-11 20:29:25
- Modify Date: 2024-01-06 17:36:55
| Name | 2-Propenoic acid, 2-chloro-, methyl ester |
|---|---|
| Synonyms |
Methyl 2-chloro-2-propenoate
2-Propenoic acid,2-chloro-,methyl ester Methyl-2-chloroacrylate methyl 2-chloropropenoate EINECS 201-298-7 2-Chloroacrylic acid,methyl ester Acrylic acid,2-chloro-,methyl ester Methyl alpha-chloroacrylate Methyl 2-chloro-2-propenate Acrylic acid, 2-chloro-, methyl ester |
| Density | 1.155g/cm3 |
|---|---|
| Boiling Point | 124.6ºC at 760 mmHg |
| Melting Point | -37 °C |
| Molecular Formula | C4H5ClO2 |
| Molecular Weight | 120.53400 |
| Flash Point | 39.7ºC |
| Exact Mass | 119.99800 |
| PSA | 26.30000 |
| LogP | 0.91190 |
| Appearance | Liquid | Clear colorless to slightly brown |
| Index of Refraction | 1.426 |
| Storage condition | 0-6°C |
Synonym:2-Chloroacrylic Acid, Methyl Ester; Methyl-Alpha-Chloroacrylate; Methyl-2-Chloroacrylate; Methyl 2-Chloro-2-Propenoate Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 10 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Flammable. Causes burns.Corrosive.Lachrymator (substance which increases the flow of tears). Potential Health Effects Eye: Causes eye burns. Lachrymator (substance which increases the flow of tears). May cause chemical conjunctivitis and corneal damage. Skin: Causes skin burns. This material is a vesicant, that is, it will induce blistering. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color. Ingestion: May cause severe and permanent damage to the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. Ingestion of large amounts may cause CNS depression. May cause systemic effects. Inhalation: May be fatal if inhaled. Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause systemic effects. May cause burning sensation in the chest. Chronic: Effects may be delayed. Section 4 - FIRST AID MEASURES Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes). Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes. Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Refrigerator/flammables. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels. Exposure Limits CAS# 80-63-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: colorless Odor: chlorine-like pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 52 deg C @ 50.00mm Hg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: 33 deg C ( 91.40 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C4H5ClO2 Molecular Weight: 120.54 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, ignition sources, excess heat, strong oxidants. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: May occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 80-63-7: AS6380000 LD50/LC50: CAS# 80-63-7: Draize test, rabbit, skin: 500 mg Severe; Inhalation, mouse: LC50 = 500 mg/m3/2H; Inhalation, rabbit: LC50 = 500 mg/m3/2H; Inhalation, rat: LC50 = 500 mg/m3/2H; Oral, rat: LD50 = 68 mg/kg; Skin, rabbit: LD50 = 270 mg/kg. Carcinogenicity: Methyl-2-Chloroacrylate - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Other No information available. Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S* Hazard Class: 3 (8) UN Number: 2924 Packing Group: III IMO Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S. Hazard Class: 3.3 (8) UN Number: 2924 Packing Group: III RID/ADR Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S. Hazard Class: 3 UN Number: 2924 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 10 Flammable. R 34 Causes burns. Safety Phrases: S 9 Keep container in a well-ventilated place. S 16 Keep away from sources of ignition - No smoking. S 25 Avoid contact with eyes. S 28 After contact with skin, wash immediately with... S 33 Take precautionary measures against static discharges. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 80-63-7: No information available. Canada CAS# 80-63-7 is listed on Canada's NDSL List. CAS# 80-63-7 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 80-63-7 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Hazard Codes | T+ |
|---|---|
| Risk Phrases | 34-26-24/25-10 |
| Safety Phrases | S16;S26;S38;S45;S36/S37/S39 |
| RIDADR | UN 2927 |
| Packaging Group | II |
| Hazard Class | 6.1(a) |
| Precursor 8 | |
|---|---|
| DownStream 10 | |
