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5327-33-3

5327-33-3 structure
5327-33-3 structure

Name 2-Acetamido-6-Methylpyridine
Synonyms N-(6-Methylpyridin-2-yl)acetamide
Acetamide, N-(6-methyl-2-pyridinyl)-
N-Acetyl-6-methyl-2-pyridinamine
2-Acetamido-6-methylpyridine
2-Picoline, 6-acetamido-
T6NJ BMV1 F1
N-(6-METHYL-2-PYRIDYL)ACETAMIDE
6-Acetamido-2-picoline
N-(6-Methyl-2-pyridinyl)acetamide
Density 1.1±0.1 g/cm3
Boiling Point 321.6±22.0 °C at 760 mmHg
Melting Point 87.0 to 91.0 °C
Molecular Formula C8H10N2O
Molecular Weight 150.178
Flash Point 148.3±22.3 °C
Exact Mass 150.079315
PSA 41.99000
LogP 0.92
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.572
Material Safety Data Sheet

Section1. Identification of the substance
2-Acetamido-6-methylpyridine
Product Name:
Synonyms:N-(6-Methylpyridin-2-yl)acetamide, 2-acetamido-6-picoline

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H315:Causes skin irritation
H319:Causes serious eye irritation
H335:May cause respiratory irritation
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:2-Acetamido-6-methylpyridine
CAS number:5327-33-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
This product should be handled only by, or under the close supervision of, those properly qualified
Handling:
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C8H10N2O
Molecular weight: 150.2

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A
HS Code 2933399090

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Literature: Journal of Organic Chemistry, , vol. 61, # 14 p. 4623 - 4633

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Literature: WO2006/21448 A1, ; Page/Page column 51-52 ;

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Literature: Journal of Physical Chemistry A, , vol. 114, # 38 p. 10421 - 10426

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Literature: US4689342 A1, ;

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Literature: Journal of Organic Chemistry, , vol. 58, # 4 p. 887 - 891

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Literature: Journal of Organic Chemistry, , vol. 58, # 4 p. 887 - 891

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Literature: Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 50, p. 536 Chem. Zentralbl., , vol. 94, # III p. 1022

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Literature: U.S. Dep. Agric. ARS, 33 - 14 <1955> 4
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%