84226-06-2

84226-06-2 structure

Name: IBZM
Chemical Name: benzamide, n-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-iodo-6-methoxy
CAS Number: 84226-06-2
Molecular Formula: C₁₅H₂₁IN₂O₃
Molecular Weight: 404.24300
Create Date: 2017-06-11 19:19:43
Modify Date: 2024-01-11 12:38:00

Name	benzamide, n-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-iodo-6-methoxy
Synonyms	IBZM (s)-benzamid N-[[(2S)-1-Ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxybenzamide S-(-)-IBZM IODOBENZAMIDE,(S)-(-)-3-IODO-2-HYDROXY-6-METHOXY-N[(1-ETHYL-2-PYRROLIDINYL)METHYL]BENZAMIDE 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide [123I]-IBZM (s)-n-(1-ethyl-2-pyrrolidinyl)methyl-2-hydroxy-3-iodo-6-methoxybenzamide (S)-N-(1-ethylpyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxybenzamide (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide

Density	1.51 g/cm3
Boiling Point	426.9ºC at 760 mmHg
Molecular Formula	C₁₅H₂₁IN₂O₃
Molecular Weight	404.24300
Flash Point	212ºC
Exact Mass	404.06000
PSA	61.80000
LogP	2.54830

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV4927050

CHEMICAL NAME :: Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-3-iodo-6 -methoxy-, (S)-

CAS REGISTRY NUMBER :: 84226-06-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H21-I-N2-O3

MOLECULAR WEIGHT :: 404.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 11,433,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - chronic pulmonary edema

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 11,433,1988

96897-88-0

~72%

84226-06-2

132448-74-9

Literature: de Paulis; Kumar; Johansson; Raemsby; Florvall; Hall; Angeby-Moeller; Ogren Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1263 - 1269

3147-64-6

84226-06-2

Literature: Journal of Medicinal Chemistry, , vol. 31, # 5 p. 1039 - 1043

1466-76-8

84226-06-2

Literature: Journal of Medicinal Chemistry, , vol. 31, # 5 p. 1039 - 1043

113452-76-9

84226-06-2

Literature: Journal of Medicinal Chemistry, , vol. 31, # 5 p. 1039 - 1043

90347-70-9

84226-06-2

Literature: Journal of Medicinal Chemistry, , vol. 28, # 9 p. 1263 - 1269

Precursor 4
3147-64-6 1466-76-8 113452-76-9 90347-70-9
DownStream 0

84226-06-2	113716-48-6
130383-75-4	1158522-08-7
940364-43-2	134104-43-1
131615-57-1	2227752-56-7
6906-52-1	930439-75-1
1018584-77-4	1375289-11-4
849349-65-1