Shanghai Nianxing Industrial Co., Ltd
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Product Name: 5（S）-HETE
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DC Chemicals Limited
China
Product Name: 5(S)-HETE
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5(S)-HETE
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70608-72-9

70608-72-9 structure

70608-72-9 structure

Name: 5-HETE
Chemical Name: 5(s)-hete
CAS Number: 70608-72-9
Molecular Formula: C₂₀H₃₂O₃
Molecular Weight: 320.466
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-07-10 22:27:43
Modify Date: 2024-01-04 11:21:26
5(S)-HETE is an endogenous metabolite present in Blood that can be used for the research of Rheumatoid Arthritis, Rhinitis and Asthma[1][2].

Name	5(s)-hete
Synonyms	5-hydroxy-6,8,11,14-eicosatetraenoicacid 5(S)-HETE [S-(E,Z,Z,Z)]-5-Hydroxy-6,8,11,14-eicosatetraenoic Acid 5-Hpete 5-HETE 5-Hydroxyicosatetraenoic acid (5S,6E,8Z,11Z,14Z)-5-Hydroxyicosa-6,8,11,14-tetraenoic acid (5S,6E,8Z,11Z,14Z)-5-Hydroxy-6,8,11,14-icosatetraenoic acid 5-hydroxyeicosatetraenoicacid 6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (5S,6E,8Z,11Z,14Z)- (S)-5-Hydroxy-6-trans-8,11,14-cis-eicosatetraenoic Acid (5S,6E,8Z,11Z,14Z)-5-Hydroxy-6,8,11,14-eicosatetraenoic acid 5-Hydroxyeicosatetraenoate

Description	5(S)-HETE is an endogenous metabolite present in Blood that can be used for the research of Rheumatoid Arthritis, Rhinitis and Asthma[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology
In Vitro	Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References	[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [2]. Chavis C, et al. A method for the measurement of plasma hydroxyeicosatetraenoic acid levels. Anal Biochem. 1999 Jun 15;271(1):105-8.

Density	1.0±0.1 g/cm3
Boiling Point	487.7±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.466
Flash Point	262.8±25.2 °C
Exact Mass	320.235138
PSA	57.53000
LogP	5.56
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.514

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JX3873000

CHEMICAL NAME :: 6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (S-(E,Z,Z,Z))-

CAS REGISTRY NUMBER :: 70608-72-9

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H32-O3

MOLECULAR WEIGHT :: 320.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 5 umol/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 10,1029,1989

Hazard Codes	F,Xi
Risk Phrases	11-36/37/38
RIDADR	UN 1170 3/PG 2