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16274-11-6

16274-11-6 structure
16274-11-6 structure
  • Name: kaempferoltetraacetate
  • Chemical Name: Kaempferol tetraacetate
  • CAS Number: 16274-11-6
  • Molecular Formula: C23H18O10
  • Molecular Weight: 454.383
  • Catalog: Natural product Flavonoids
  • Create Date: 2017-09-30 12:29:11
  • Modify Date: 2024-02-03 00:54:38
  • Kaempferol tetraacetate (AF33) is a natural product. Kaempferol tetraacetate shows cytotoxicity[1][2].

Name Kaempferol tetraacetate
Synonyms 4H-1-Benzopyran-4-one, 3,5,7-tris(acetyloxy)-2-[4-(acetyloxy)phenyl]-
2-(4-Acetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate
Description Kaempferol tetraacetate (AF33) is a natural product. Kaempferol tetraacetate shows cytotoxicity[1][2].
Related Catalog
In Vitro Kaempferol tetraacetate (compound 1a) (0-100 µM; 72 h) 显示细胞毒性,对 HL-60、U937、SK-MEL-1 细胞的 IC50 值分别为 45、48、37 µM [2]。 Cell Cytotoxicity Assay[2] Cell Line: HL-60, U937, SK-MEL-1 cells Concentration: 0-100 µM Incubation Time: 72 h Result: Showed cytotoxicity with IC50s of 45, 48, 37 µM for HL-60, U937, SK-MEL-1 cells, respectively.
References

[1]. Mei Q, et al. Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates. Beilstein J Org Chem. 2015 Feb 25;11:288-93.  

[2]. Díaz JG, et al. Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana. Planta Med. 2008 Feb;74(2):171-4.  

Density 1.4±0.1 g/cm3
Boiling Point 609.7±55.0 °C at 760 mmHg
Molecular Formula C23H18O10
Molecular Weight 454.383
Flash Point 263.9±31.5 °C
Exact Mass 454.089996
PSA 135.41000
LogP 1.16
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.605
Hazard Codes Xi