Name | h-thr-thr-tyr-ala-asp-phe-ile-ala-ser-gly-arg-thr-gly-arg-arg-asn-ala-ile-nh2 |
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Synonyms |
PKI (5-22),AMIDE
CAMP-DEPENDENT PROTEIN KINASE INHIBITOR (5-22) AMIDE PKI-a (5-22) aMide (huMan,Mouse,rabbit,rat),Wiptide cAMP-Dependent Protein Kinase Inhibitor (5-22),amide,Wiptide WIPTIDE PROTEIN KINASE A INHIBITOR (5-22) AMIDE TTYADFIASGRTGRRNAI-NH2 CAMP DEPENDENT PK INHIBITOR (5-22) AMIDE PKA INHIBITOR (5-22) AMIDE THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2 THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP: TTYADFIASGRTGRRNAIHD |
Description | PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the cyclic AMP-dependent protein kinase (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors[1][2]. |
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Related Catalog | |
In Vitro | PKI(5-22)amide (1 μM; 1 min) fails to block CRF1 receptor (100 nM; 30 min) desensitization in Y-79 cells permeabilized with Streptolysin O (HY-135416)[1]. |
References |
Molecular Formula | C84H137N29O26 |
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Molecular Weight | 1969.17000 |
Exact Mass | 1968.03000 |
PSA | 931.05000 |