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1820-81-1

1820-81-1 structure
1820-81-1 structure
  • Name: 5-Chlorouracil
  • Chemical Name: 5-chlorouracil
  • CAS Number: 1820-81-1
  • Molecular Formula: C4H3ClN2O2
  • Molecular Weight: 146.53
  • Catalog: Biochemical Nucleoside drugs Nucleotides and their analogues
  • Create Date: 2018-03-17 08:00:00
  • Modify Date: 2024-01-02 08:48:52
  • 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Name 5-chlorouracil
Synonyms 5-Chloropyrimidine-2,4(1H,3H)-dione
2,4(1H,3H)-Pyrimidinedione,5-chloro
5-Chlorouracil
5-chloro-2,4-dioxopyrimidine
5-chloro-1H-pyrimidine-2,4-dione
4-chlorouracil
5-Chloro-2,4(1H,3H)-pyrimidinedione
EINECS 217-339-7
5-chloro-uracil
Uracil,5-chloro
2,4(1H,3H)-Pyrimidinedione, 5-chloro-
5-Chloro-2,4-dihydroxypyrimidine
MFCD00006019
5-Chloropyrimidine-2,4-diol
Description 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 5-氯尿嘧啶是嘧啶核苷碱基尿嘧啶的氯化衍生物。在体内,它会转化为具有致突变性和遗传毒性的氯脱氧尿苷。1 尿嘧啶在无细胞髓过氧化物酶、过氧化物和氯化物系统中的 5 位被氯化,在该系统中形成次氯酸 2 5-氯尿嘧啶已在体外和体外用佛波醇 12-肉豆蔻酸酯 13-乙酸酯刺激的人嗜中性粒细胞中被发现从浅表感染部位分离的炎性人体渗出物。在角叉菜胶诱导的炎症大鼠模型和患者来源的人动脉粥样硬化主动脉组织中,从炎症部位分离的渗出液中 5-氯尿嘧啶的水平增加。3,4 参考资料
Density 1.6±0.1 g/cm3
Melting Point >300 °C(lit.)
Molecular Formula C4H3ClN2O2
Molecular Weight 146.53
Flash Point 203.9ºC
Exact Mass 145.988312
PSA 65.72000
LogP -0.52
Vapour Pressure 1.98E-07mmHg at 25°C
Index of Refraction 1.587
Storage condition Refrigerator

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ9410000
CHEMICAL NAME :
Uracil, 5-chloro-
CAS REGISTRY NUMBER :
1820-81-1
LAST UPDATED :
199410
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C4-H3-Cl-N2-O2
MOLECULAR WEIGHT :
146.54
WISWESSER LINE NOTATION :
T6MVMVJ FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
50 mg/L/1H
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 38,371,1976
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YQ9410000
HS Code 29335995
HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%