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6835-16-1

6835-16-1 structure
6835-16-1 structure
  • Name: Hyoscyamine Sulfate
  • Chemical Name: hyoscyamine sulfate
  • CAS Number: 6835-16-1
  • Molecular Formula: C34H52N2O12S
  • Molecular Weight: 712.848
  • Create Date: 2018-02-22 08:00:00
  • Modify Date: 2024-01-14 19:02:55
  • Hyoscyamine Sulfate

Name hyoscyamine sulfate
Synonyms HYOSCYAMINESULFATE,USP
Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-, sulfate, hydrate (2:1:2) (salt)
HYOSCYAMINE SULPHATE
Hyoscyamine sulphate hydrate
HOSCYAMINE SULFATE USP
DL-tropic acid tropane-3endo-yl ester,sulfate
DL-Tropasaeure-tropan-3endo-ylester,Sulfat
Egacene
8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate sulfate hydrate (2:1:2)
Molecular Formula C34H52N2O12S
Molecular Weight 712.848
Exact Mass 712.324097
PSA 200.98000
LogP 4.03700
Storage condition 20°C

Section 1. Chemical Product and Company Identification
Hyoscyamine sulfate
Common Name/
Trade Name
Hyoscyamine sulfate

Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water
for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
Skin ContactIn case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash
clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Serious InhalationNot available.
IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to
an unconscious person. If large quantities of this material are swallowed, call a physician immediately.
Loosen tight clothing such as a collar, tie, belt or waistband.
Serious IngestionNot available.

Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Not available.
Flash Points
Flammable LimitsNot available.
Products of CombustionThese products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...).
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards in
Risks of explosion of the product in presence of static discharge: Not available.
Presence of Various
Substances
Fire Fighting MediaSMALL FIRE: Use DRY chemical powder.
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks onNot available.
Fire Hazards
Special Remarks on Explosion Not available.
Hazards

Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large SpillPoisonous solid.
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray
to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all
surface and allow to evacuate through the sanitary system.
Hyoscyamine sulfate

Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do
not ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice
immediately and show the container or the label.
Keep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in
Storage
light-resistant containers.

Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels
below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
exposure to airborne contaminants below the exposure limit.
Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
a Large Spillused to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product.
Exposure LimitsNot available.

Section 9. Physical and Chemical Properties
Physical state and appearance Solid.OdorNot available.
Not available.
Taste
Molecular Weight712.85 g/mole
Not available.
Color
Not available.
pH (1% soln/water)
Boiling PointDecomposes.
206°C (402.8°F)
Melting Point
Critical TemperatureNot available.
Specific GravityNot available.
Vapor PressureNot applicable.
Vapor DensityNot available.
Not available.
Volatility
Odor ThresholdNot available.
Not available.
Water/Oil Dist. Coeff.
Ionicity (in Water)Not available.
Dispersion PropertiesSee solubility in water.
SolubilitySoluble in cold water.

Section 10. Stability and Reactivity Data
StabilityThe product is stable.
Instability TemperatureNot available.
Conditions of InstabilityExcess heat
Incompatibility with various Not available.
substances
CorrosivityNon-corrosive in presence of glass.
Special Remarks onNot available.
Reactivity
Hyoscyamine sulfate
Not available.
Special Remarks on
Corrosivity
PolymerizationWill not occur.

Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
LD50: Not available.
Toxicity to Animals
LC50: Not available.
Chronic Effects on Humans Not available.
Hazardous in case of ingestion.
Other Toxic Effects on
Slightly hazardous in case of skin contact (irritant), of inhalation.
Humans
Special Remarks onNot available.
Toxicity to Animals
Special Remarks onNot available.
Chronic Effects on Humans
Special Remarks on otherMay cause skin, eye, and respiratory tract irritation.
Toxic Effects on HumansHarmful if swallowed. May cause constipation. May affect behavior/central nervous system, respiratory
system (dyspnea), cardiovascular system, vision. An anticholinergic agent. It can cause blurred vision,
photophobia, vasodilation, rapid and weak pulse, tachydardia, hyperpyrexia, excitement, muscular
incoordination, convulsions, agitation, restlessness, disturbed gait and speech, hallucinations, delirium, and
pupil dilation, bradycardia.

Section 12. Ecological Information
EcotoxicityNot available.
BOD5 and CODNot available.
Possibly hazardous short term degradation products are not likely. However, long term degradation
Products of Biodegradation
products may arise.
The products of degradation are less toxic than the product itself.
Toxicity of the Products
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation

Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.

Section 14. Transport Information
DOT ClassificationCLASS 6.1: Poisonous material.
UNNA: 1544 : Alkaloid salt, solid, n.o.s. (Hyoscyamine sulfate) PG: III
Identification
Special Provisions forNot available.
Transport
DOT (Pictograms)
Hyoscyamine sulfate

Section 15. Other Regulatory Information and Pictograms
No products were found.
Federal and State
Regulations
CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has
Proposition 65found to cause cancer which would require a warning under the statute: No products were found.
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has
found to cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
Other Classifications
DSCL (EEC)R25- Toxic if swallowed.S45- In case of accident or if you feel unwell,
seek medical advice immediately (show the
label where possible).
Health Hazard
HMIS (U.S.A.)2 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
2 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
Safety glasses.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300 + H330
Precautionary Statements Missing Phrase - N15.00950417-P260-P304 + P340 + P310-P403 + P233
RIDADR UN 1544PSN1 6.1 / PGII