52248-03-0

52248-03-0 structure

Name: S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt
Chemical Name: 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-Adenosine tosylate
CAS Number: 52248-03-0
Molecular Formula: C₂₂H₃₀N₆O₈S₂
Molecular Weight: 570.639
Catalog: Research Areas Cancer
Create Date: 2018-03-01 08:00:00
Modify Date: 2024-01-06 11:59:16
S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3].

Name	5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-Adenosine tosylate
Synonyms	[(3S)-3-Amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl}methylsulfonium 4-methylbenzenesulfonate SAM p-toluenesulfonate salt Methionine,S-adenosyl-,DL S-Adenosyl-DL-methionine S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt [(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium,4-methylbenzenesulfonate S-Adenosyl methionione methyl-S-adenosyl-L-Met S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt AdoMet SAM p-toluenesulfonate salt

Description	S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	Human Endogenous Metabolite
References	[1]. G M Bressa. et al. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14. [2]. Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6. [3]. Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92(4):1515-42.