S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt

Modify Date: 2024-01-06 11:59:16

S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt Structure
S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt structure
Common Name S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt
CAS Number 52248-03-0 Molecular Weight 570.639
Density N/A Boiling Point N/A
Molecular Formula C22H30N6O8S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt


S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3].

 Names

Name 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-Adenosine tosylate
Synonym More Synonyms

  Biological Activity

Description S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. G M Bressa. et al. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14.  

[2]. Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6.  

[3]. Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92(4):1515-42.  

 Chemical & Physical Properties

Molecular Formula C22H30N6O8S2
Molecular Weight 570.639
Exact Mass 570.156677
PSA 273.51000
LogP 1.33920

 Synonyms

[(3S)-3-Amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl}methylsulfonium 4-methylbenzenesulfonate
SAM p-toluenesulfonate salt
Methionine,S-adenosyl-,DL
S-Adenosyl-DL-methionine
S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
[(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium,4-methylbenzenesulfonate
S-Adenosyl methionione
methyl-S-adenosyl-L-Met
S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt
AdoMet SAM p-toluenesulfonate salt
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