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123940-93-2

123940-93-2 structure
123940-93-2 structure
  • Name: ω-3 Arachidonic Acid ethyl ester
  • Chemical Name: ethyl (8Z,11Z,14Z,17Z)-icosatetraenoate
  • CAS Number: 123940-93-2
  • Molecular Formula: C22H36O2
  • Molecular Weight: 332.520
  • Catalog: Research Areas Others
  • Create Date: 2017-03-28 11:37:08
  • Modify Date: 2024-01-13 19:02:14
  • omega-3 Arachidonic Acid ethyl ester is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.

Name ethyl (8Z,11Z,14Z,17Z)-icosatetraenoate
Synonyms Ethyl (8Z,11Z,14Z,17Z)-8,11,14,17-icosatetraenoate
.ω.-3 Arachidonic Acid ethyl ester
8,11,14,17-Eicosatetraenoic acid, ethyl ester, (8Z,11Z,14Z,17Z)-
Description omega-3 Arachidonic Acid ethyl ester is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.
Related Catalog
Density 0.9±0.1 g/cm3
Boiling Point 418.1±24.0 °C at 760 mmHg
Molecular Formula C22H36O2
Molecular Weight 332.520
Flash Point 100.7±21.2 °C
Exact Mass 332.271515
PSA 26.30000
LogP 7.88
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.485

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JX3855100
CHEMICAL NAME :
8,11,14,17-Eicosatetraenoic acid, ethyl ester, (all Z)-
CAS REGISTRY NUMBER :
123940-93-2
LAST UPDATED :
199106
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H36-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,801,1989
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,801,1989