29809-15-2

29809-15-2 structure

Name: Meconin-d3
Chemical Name: 6-methoxy-7-(trideuteriomethoxy)-3H-2-benzofuran-1-one
CAS Number: 29809-15-2
Molecular Formula: C₁₀H₇D₃O₄
Molecular Weight: 197.202
Catalog: Research Areas Metabolic Disease
Create Date: 2017-06-24 05:48:38
Modify Date: 2024-01-03 18:27:23
Meconin-d3 is the deuterium labeled Meconine. Meconine is an endogenous metabolite[1][2].

Name	6-methoxy-7-(trideuteriomethoxy)-3H-2-benzofuran-1-one
Synonyms	Meconin-d3 1(3H)-Isobenzofuranone, 6-methoxy-7-(methyl-d-oxy)- Meconic Lactone-d3 Opianyl-d3 6-Methoxy-7-[(H)methyloxy]-2-benzofuran-1(3H)-one 6,7-Dimethoxyphthalide-d3

Description	Meconin-d3 is the deuterium labeled Meconine. Meconine is an endogenous metabolite[1][2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Jones JT, et al. Detection of codeine, morphine, 6-monoacetylmorphine, and meconin in human umbilical cord tissue: method validation and evidence of in utero heroin exposure. Ther Drug Monit. 2015;37(1):45-52. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.