313682-08-5

313682-08-5 structure

Name: Brecanavir
Chemical Name: [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate
CAS Number: 313682-08-5
Molecular Formula: C₃₃H₄₁N₃O₁₀S₂
Molecular Weight: 703.82300
Catalog: Signaling Pathways Metabolic Enzyme/Protease HIV Protease
Create Date: 2017-10-02 15:34:02
Modify Date: 2024-01-09 15:10:20
Brecanavir (GW640385) is a novel, potent HIV protease inhibitor.

Name	[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate
Synonyms	Brecanavir 2fdd 2fde GW0385

Description	Brecanavir (GW640385) is a novel, potent HIV protease inhibitor.
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease
References	[1]. Ford SL, Reddy YS, Anderson MT, et al. Single-dose safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus protease inhibitor. Antimicrob Agents Chemother. 2006;50(6):2201-2206. [2]. Reddy YS, Ford SL, Anderson MT, Murray SC, Ng-Cashin J, Johnson MA. Safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus type 1 protease inhibitor, following repeat administration with and without ritonavir in healthy adult subjects. Antimicrob Agents Chemother. 2007;51(4):1202-1208.

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