21255-69-6

21255-69-6 structure

Name: O-Desmethylangolensin
Chemical Name: 1-(2,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
CAS Number: 21255-69-6
Molecular Formula: C₁₅H₁₄O₄
Molecular Weight: 258.26900
Catalog: Research Areas Metabolic Disease
Create Date: 2016-09-04 12:26:14
Modify Date: 2024-01-06 14:06:18
O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity[1][2].

Name	1-(2,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
Synonyms	O-Desmethylangolensin o-demethylangolensin O-Demethylangolesin

Description	O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
In Vitro	O-Desmethylangolensin (O-DMA) inhibits the growth of HepG2 cells at higher doses (~30% decrease at 75 μM)[2].
References	[1]. Elizabeth J Reverri, et al. Metabolomics reveals differences between three daidzein metabolizing phenotypes in adults with cardiometabolic risk factors. Mol Nutr Food Res. 2017 Jan;61(1). [2]. Eun Jeong Choi, et al. The antioxidant activity of daidzein metabolites, O‑desmethylangolensin and equol, in HepG2 cells. Mol Med Rep. 2014 Jan;9(1):328-32.

HS Code	2914501900

938-96-5

108-46-3

~82%

21255-69-6

Literature: Goto, Hideyuki; Terao, Yoshiyasu; Akai, Shuji Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 4 p. 346 - 360

486-66-8

~40%

21255-69-6

Literature: Salakka; Waehaelae Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 18 p. 2601 - 2604

HS Code	2914501900
Summary	2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%