11006-31-8

11006-31-8 structure

Name: Monazomycin
Chemical Name: monoazomycin
CAS Number: 11006-31-8
Molecular Formula: C₇₂H₁₃₃NO₂₂
Molecular Weight: 1364.82000
Catalog: Research Areas Infection
Create Date: 2017-04-28 02:57:46
Modify Date: 2024-01-02 21:40:45
Monazomycin is a polyene-like antibiotic produced by Streptomyces. Monazomycin molecular weight is about 1200[1].

Name	monoazomycin
Synonyms	MONAZOMYCIN Monazomycin

Description	Monazomycin is a polyene-like antibiotic produced by Streptomyces. Monazomycin molecular weight is about 1200[1].
Related Catalog	Research Areas >> Infection
In Vitro	Monazomycin is an antibiotic produced by Streptomyces. Its molecular weight is about 1200, and is related to that of polyene antibiotics. Monazomycin has an amino group that gives a positive charge to the molecule at neutral pH. When monazomycin is added in micromolar amounts to one side of a bilayer, membrane conductance becomes strongly voltage-dependent. Monazomycin is present in the solution in the form of relatively hydrophilic clusters and is adsorbed as such on top of the lipid bilayer, penetration into the bilayer following a potential jump is assumed to be preceded by a potential-independent disaggregation of the adsorbed clusters into adsorbed monomers[1].
References	[1]. Becucci L, et al. Kinetics of channel formation in bilayer lipid membranes (BLMs) and tethered BLMs: monazomycin and melittin. Langmuir. 2007;23(10):5601-5608.