5657-61-4

5657-61-4 structure

Name: E 537
Chemical Name: N-hydroxypyridine-3-carboxamide
CAS Number: 5657-61-4
Molecular Formula: C₆H₆N₂O₂
Molecular Weight: 138.12400
Create Date: 2018-03-25 08:00:00
Modify Date: 2024-04-02 17:14:46

Name	N-hydroxypyridine-3-carboxamide
Synonyms	Nicoxamat 3-picolinehydroxamic acid E 537 3-pyridinehydroxamic acid nicotinic acid hydroxamate N-Hydroxy-3-pyridinecarboxamide Nicotinohydroximic acid Nicotinohydroxamsaeure N-Hydroxynicotinamid Nicotine hydroxamic acid nicotinohydroxamic acid 3-Pyridinecarboxamide,N-hydroxy 3-pyridinecarbohydroxamic acid Nicotinylhydroxamic acid

Density	1.328g/cm3
Molecular Formula	C₆H₆N₂O₂
Molecular Weight	138.12400
Exact Mass	138.04300
PSA	62.22000
LogP	0.59150
Index of Refraction	1.585

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US4666100

CHEMICAL NAME :: 3-Pyridinecarboxamide, N-hydroxy-

CAS REGISTRY NUMBER :: 5657-61-4

BEILSTEIN REFERENCE NO. :: 0003657

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H6-N2-O2

MOLECULAR WEIGHT :: 138.14

WISWESSER LINE NOTATION :: T6NJ CVMQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 1 mmol/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 29,1275,1980

Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	26-36

614-18-6

5657-61-4

Literature: Shavel et al. Journal of the American Pharmaceutical Association (1912-1977), 1953 , vol. 42, p. 402,405 Full Text Show Details Anderson et al. Journal of Biological Chemistry, 1959 , vol. 234, p. 1219

93-60-7

~66%

5657-61-4

Literature: Mulcahy, Clodagh; Dolgushin, Fedor M.; Krot, Krystyna A.; Griffith, Darren; Marmion, Celine J. Dalton Transactions, 2005 , # 11 p. 1993 - 1998 Title/Abstract Full Text View citing articles Show Details Mulcahy, Clodagh; Krot, Krystyna A.; Griffith, Darren M.; Suponitsky, Kyrill Yu.; Starikova, Zoya A.; Marmion, Celine J. European Journal of Inorganic Chemistry, 2007 , # 10 p. 1373 - 1380

Precursor 2
614-18-6 93-60-7
DownStream 3
462-08-8 13114-65-3 5434-60-6

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