73836-78-9

73836-78-9 structure

Name: Leukotriene D4
Chemical Name: leukotriene D4
CAS Number: 73836-78-9
Molecular Formula: C₂₅H₄₀N₂O₆S
Molecular Weight: 496.660
Create Date: 2017-03-28 07:22:47
Modify Date: 2024-01-06 09:18:23
Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.

Name	leukotriene D4
Synonyms	(5S,6R,7E,9E,11Z,14Z)-6-({(2R,3Z)-2-Amino-3-[(carboxymethyl)imino]-3-hydroxypropyl}sulfanyl)-5-hydroxy-7,9,11,14-icosatetraenoic acid Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl- Leukotriene D4 LTD4 S-[(4S,5R,6E,8E,10Z,13Z)-1-Carboxy-4-hydroxy-6,8,10,13-nonadecatetraen-5-yl]-L-cysteinylglycine 7,9,11,14-Eicosatetraenoic acid, 6-[[(2R,3Z)-2-amino-3-[(carboxymethyl)imino]-3-hydroxypropyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11Z,14Z)- leukotriened

Description	Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.

CHEMICAL NAME :: Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecat etraenyl)-L-cysteinyl )-, (R- (R*,S*-(E,E,Z,Z)))-

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 51,5573,1991

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310 + P330-P302 + P352 + P312-P370 + P378
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	F: Flammable;T: Toxic;
Risk Phrases	R11
Safety Phrases	7-16-36/37-45
RIDADR	UN 1230 3/PG 2