Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Nsc-77053
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Nsc-77053
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-(9H-fluorene-2-carbonyl)benzoic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

77308-57-7

77308-57-7 structure

77308-57-7 structure

Name: NSC-77053
Chemical Name: 2-(9H-fluorene-2-carbonyl)benzoic acid
CAS Number: 77308-57-7
Molecular Formula: C₂₁H₁₄O₃
Molecular Weight: 314.33400
Catalog: Research Areas Others
Create Date: 2016-01-14 14:15:28
Modify Date: 2024-02-01 19:13:15
NSC-77053 is a potent BoNT/E inhibitor with an IC50 and a Ki of 2.4 μM and 1.29 μM, respectively[1].

Name	2-(9H-fluorene-2-carbonyl)benzoic acid

Description	NSC-77053 is a potent BoNT/E inhibitor with an IC50 and a Ki of 2.4 μM and 1.29 μM, respectively[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	IC50: 2.4 μM (BoNT/E)[1]
References	[1]. Yuchen Zhou, et al. Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity. Bioorg Med Chem. 2016 Oct 15;24(20):4875-4889.

Density	1.315g/cm3
Boiling Point	586.6ºC at 760 mmHg
Molecular Formula	C₂₁H₁₄O₃
Molecular Weight	314.33400
Flash Point	322.6ºC
Exact Mass	314.09400
PSA	54.37000
LogP	4.18700
Index of Refraction	1.682

85-44-9 structure

85-44-9

86-73-7 structure

86-73-7

~79%

77308-57-7 structure

77308-57-7

Literature: Guilhemat, Robert; Pereyre, Michel; Petraud, Michel Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 7-8 p. 334 - 344

Precursor 2
85-44-9 86-73-7
DownStream 2
86-73-7 72834-21-0