37497-00-0

37497-00-0 structure
37497-00-0 structure
  • Name: 4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine
  • Chemical Name: 4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine
  • CAS Number: 37497-00-0
  • Molecular Formula: C7H8N4OS
  • Molecular Weight: 196.23000
  • Create Date: 2018-06-22 17:14:49
  • Modify Date: 2023-02-06 14:28:33

Name 4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine
Synonyms 4-Methoxy-7H-pyrimido(4,5-b)(1,4)thiazin-6-amine
Thomizin-Base
4-Methoxy-6-aminopyrimido<4,5-b>-1,4-thiazin
4-Methoxy-6-aminopyrimido<4,5-b>(1,4)thiazine
7H-Pyrimido(4,5-b)(1,4)thiazine,6-amino-4-methoxy
6-Amino-4-methoxy-7H-pyrimido(4,5-b)(1,4)thiazine
4-methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-ylamine
Density 1.64g/cm3
Boiling Point 456.8ºC at 760 mmHg
Molecular Formula C7H8N4OS
Molecular Weight 196.23000
Flash Point 230.1ºC
Exact Mass 196.04200
PSA 98.69000
LogP 0.71550
Index of Refraction 1.774

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UW7864000
CHEMICAL NAME :
7H-Pyrimido(4,5-b)(1,4)thiazine, 6-amino-4-methoxy-
CAS REGISTRY NUMBER :
37497-00-0
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H8-N4-O-S
MOLECULAR WEIGHT :
196.25
WISWESSER LINE NOTATION :
T66 BN DN GN JS IHJ EO1 HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,1205,1977
HS Code 2934999090

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37497-00-0 structure

37497-00-0

Literature: Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 8, p. 859 - 863 Khimiya Geterotsiklicheskikh Soedinenii, , vol. 8, # 7 p. 944 - 948
Precursor  2

DownStream  0

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%