Henan Tianfu Chemical Co., Ltd.
China
Product Name: R(-)-METHADONE HYDROCHLORIDE OPIOID AGON IST
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

125-58-6

125-58-6 structure

Name: (6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one
Chemical Name: (6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one
CAS Number: 125-58-6
Molecular Formula: C₂₁H₂₇NO
Molecular Weight: 309.44500
Create Date: 2018-08-29 18:36:37
Modify Date: 2024-01-05 16:34:35

Name	(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one
Synonyms	Levothyl Levadone l-Polamivet Polamivet l-methadone L-Polamidon Levomethadone

Density	1.009g/cm3
Boiling Point	423.7ºC at 760mmHg
Melting Point	99-100ºC
Molecular Formula	C₂₁H₂₇NO
Molecular Weight	309.44500
Flash Point	126.5ºC
Exact Mass	309.20900
PSA	20.31000
LogP	4.29200
Vapour Pressure	2.2E-07mmHg at 25°C
Index of Refraction	1.538

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MJ5990000

CHEMICAL NAME :: 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, L-

CAS REGISTRY NUMBER :: 125-58-6

BEILSTEIN REFERENCE NO. :: 3213668

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C21-H27-N-O

MOLECULAR WEIGHT :: 309.49

WISWESSER LINE NOTATION :: 2VXR&R&1Y1&N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 97 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 26500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1600 ug/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - other effects on male

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - rat Testis

DOSE/DURATION :: 50 umol/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,123,1978

HS Code	2922399090

76-99-3

125-58-6

Literature: Justus Liebigs Annalen der Chemie, , vol. 561, p. 52,76 Journal of Organic Chemistry, , vol. 13, p. 191 Journal of the American Chemical Society, , vol. 70, p. 4194 Journal of the American Chemical Society, , vol. 71, p. 2935

86-29-3

125-58-6

Literature: Justus Liebigs Annalen der Chemie, , vol. 561, p. 52,76

125-79-1

125-58-6

Literature: Journal of the Chemical Society, , p. 648,651

7576-16-1

925-90-6

125-58-6

Literature: Journal of the Chemical Society, , p. 648,651

Precursor 5
76-99-3 86-29-3 125-79-1 7576-16-1
925-90-6
DownStream 0

HS Code	2922399090
Summary	2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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