74889-51-3

registration deadline.
CAS-No.: 74889-51-3
Relevant identified uses of the substance or mixture and uses advised against
Identified uses: Laboratory chemicals, Manufacture of substances

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SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Inhalation (Category 2), H330
Acute toxicity, Dermal (Category 1), H310
Acute toxicity, Oral (Category 2), H300
Acute aquatic toxicity (Category 1), H400
Chronic aquatic toxicity (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
T+ Very toxicR26/27/28
R32
N Dangerous for theR50/53
environment
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal wordDanger
Hazard statement(s)
H300Fatal if swallowed.
H310Fatal in contact with skin.
H330Fatal if inhaled.
H410Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P260Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P264Wash hands thoroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/ protective clothing.
P284Wear respiratory protection.
P301 + P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/
physician.
Supplemental Hazard information (EU)
EUH032Contact with acids liberates very toxic gas.
Other hazards - none

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SECTION 3: Composition/information on ingredients
Substances
Formula: 13CK15N
Molecular Weight: 67,10 g/mol
CAS-No.: 74889-51-3
Hazardous ingredients according to Regulation (EC) No 1272/2008
ComponentClassificationConcentration
Potassium cyanide-13C,15N
CAS-No.74889-51-3Acute Tox. 2; Acute Tox. 1;<= 100 %
Aquatic Acute 1; Aquatic
Chronic 1; H300 + H310 +
H330, H410, EUH032
Hazardous ingredients according to Directive 1999/45/EC
ComponentClassificationConcentration
Potassium cyanide-13C,15N
CAS-No.74889-51-3T+, N, R26/27/28 - R32 -<= 100 %
R50/53
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take
victim immediately to hospital. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
no data available

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SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Dry powder
Special hazards arising from the substance or mixture
no data available
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

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SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Do not flush with water. Keep
in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.

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SECTION 7: Handling and storage
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Store under inert gas. hygroscopic
Never allow product to get in contact with water during storage. Do not store near acids.
Air, light, and moisture sensitive.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must
be evaluated by an industrial hygienist and safety officer familiar with the specific situation of
anticipated use by our customers. It should not be construed as offering an approval for any
specific use scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
the environment must be avoided.

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SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) AppearanceForm: solid
b) Odourno data available
c) Odour Thresholdno data available
d) pH11,5 at 20 g/l at 20 °C
e) Melting point/freezingMelting point/range: > 300 °C - lit.
point
f) Initial boiling point and 1.625 °C
boiling range
g) Flash pointno data available
h) Evapouration rateno data available
i) Flammability (solid, gas) no data available
j) Upper/lowerno data available
flammability or
explosive limits
k) Vapour pressureno data available
l) Vapour densityno data available
m) Relative density1,520 g/cm3
n) Water solubilityno data available
o) Partition coefficient: n- log Pow: 0,44
octanol/water
p) Auto-ignitionno data available
temperature
q) Decompositionno data available
temperature
r) Viscosityno data available
s) Explosive propertiesno data available
t) Oxidizing propertiesno data available
Other safety information
no data available

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SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Light.
Stable under recommended storage conditions.
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Acids, Strong oxidizing agents, Iodine, permanganates, e.g. potassium permanganate, Peroxides, Metallic
salts, Chloral hydrate, Alkaloids, Chlorates
Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5

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SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
LDLO Oral - Human - 2,857 mg/kg
LD50 Oral - mouse - 8,5 mg/kg
LD50 Oral - rabbit - 5 mg/kg
LD50 Oral - rat - 6 mg/kg
Inhalation: no data available
Dermal: no data available
LD50 Intraperitoneal - rat - 4 mg/kg
Remarks: Lungs, Thorax, or Respiration:Other changes.
LD50 Subcutaneous - rat - 7,814 mg/kg
LD50 Intravenous - rat - 3,6 mg/kg
Remarks: Behavioral:Altered sleep time (including change in righting reflex). Behavioral:Convulsions or
effect on seizure threshold. Lungs, Thorax, or Respiration:Dyspnea.
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitisation
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC:No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Additional Information
RTECS: Not available
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and
skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi,
pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath,
Headache, Nausea, Vomiting, Lung irritation, Cyanosis, Central nervous system depression, To the best of
our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

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SECTION 12: Ecological information
Toxicity
Toxicity to fishLC50 - Oncorhynchus mykiss (rainbow trout) - 0,052 mg/l - 96,0 h
LC50 - Lepomis macrochirus - 0,45 mg/l - 96,0 h
Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - 2 mg/l - 48 h
other aquatic
invertebrates
EC50 - Daphnia magna (Water flea) - 0,53 mg/l - 24 h
EC50 - Daphnia magna (Water flea) - 2 mg/l - 48 h
EC50 - Daphnia magna (Water flea) - 0,53 mg/l - 24 h
Toxicity to algaeIC50 - Scenedesmus quadricauda (Green algae) - 0,03 mg/l - 192 h
Toxicity to bacteria- Bacteria - 0,6 - 2,3 mg/l - 0,5 h
Persistence and degradability
no data available
Chemical Oxygen< 1 mg/g
Demand (COD)
Bioaccumulative potential
BioaccumulationOncorhynchus mykiss (rainbow trout) - 16 Weeks
- 20,8 µg/l
Bioconcentration factor (BCF): 170
Mobility in soil
no data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
Very toxic to aquatic life with long lasting effects.

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SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

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SECTION 14: Transport information
UN number
ADR/RID: 1680IMDG: 1680IATA: 1680
UN proper shipping name
ADR/RID: POTASSIUM CYANIDE, SOLID
IMDG: POTASSIUM CYANIDE, SOLID
IATA:Potassium cyanide, solid
Transport hazard class(es)
ADR/RID: 6.1IMDG: 6.1IATA: 6.1
Packaging group
ADR/RID: IIMDG: IIATA: I
Environmental hazards
ADR/RID: yesIMDG Marine pollutant: yesIATA: no
Special precautions for user
no data available

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SECTION 15 - REGULATORY INFORMATION
N/A

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SECTION 16 - ADDITIONAL INFORMATION
N/A