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143120-46-1

143120-46-1 structure
143120-46-1 structure
  • Name: Neotuberostemonine
  • Chemical Name: (2S,7aR,8R,8aR,11S,11aR,11bS,11cR)-8-Ethyl-11-methyl-2-[(2S,4S)-4 -methyl-5-oxotetrahydro-2-furanyl]dodecahydroazepino[3,2,1-hi]fur o[3,2-e]indol-10(2H)-one
  • CAS Number: 143120-46-1
  • Molecular Formula: C22H33NO4
  • Molecular Weight: 375.502
  • Catalog: Natural product Alkaloid
  • Create Date: 2017-07-08 06:16:13
  • Modify Date: 2024-01-02 17:44:27
  • Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages[1].

Name (2S,7aR,8R,8aR,11S,11aR,11bS,11cR)-8-Ethyl-11-methyl-2-[(2S,4S)-4 -methyl-5-oxotetrahydro-2-furanyl]dodecahydroazepino[3,2,1-hi]fur o[3,2-e]indol-10(2H)-one
Synonyms Tuberostemonin
(2S,7aR,8R,8aR,11S,11aR,11bS,11cR)-8-Ethyl-11-methyl-2-[(2S,4S)-4-methyl-5-oxotetrahydro-2-furanyl]dodecahydroazepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one
Tubastatin A
Azepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one, 8-ethyldodecahydro-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (2S,7aR,8R,8aR,11S,11aR,11bS,11cR)-
TSLDASIIWAMMQN
Neotuberostemonine
Description Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages[1].
Related Catalog
References

[1]. Xiang J, et al. Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages. Int Immunopharmacol. 2016 Jul;36:158-164.

Density 1.2±0.1 g/cm3
Boiling Point 554.2±50.0 °C at 760 mmHg
Molecular Formula C22H33NO4
Molecular Weight 375.502
Flash Point 289.0±30.1 °C
Exact Mass 375.240967
PSA 55.84000
LogP 2.28
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.556
Hazard Codes Xi