Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Sappanchalcone
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: Sappanchalcone
Price: ￥3400.0/5mg
Purity: 97.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Sappanchalcone
Price: ￥4640.0/5mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Sappanchalcone
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: SAPPANCHALCONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

94344-54-4

94344-54-4 structure

94344-54-4 structure

Name: Sappanchalcone
Chemical Name: sappanchalcone
CAS Number: 94344-54-4
Molecular Formula: C₁₆H₁₄O₅
Molecular Weight: 286.279
Catalog: Natural product Chalcone
Create Date: 2018-07-24 18:48:11
Modify Date: 2024-01-02 15:19:18
Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1].

Name	sappanchalcone
Synonyms	(2E)-3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-2-propen-1-one 2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-, (E)- 2'-Methoxy-3,4,4'-trihydroxychalcone 3,4,4'-Trihydroxy-2'-methoxychalcone sapphalcone (E)-3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)prop-2-en-1-one 2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-, (2E)- Sappan chalcone

Description	Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Sappanchalcone has a statistically significant effect on HCT116 cells than on SW480 cells (IC50= 37.33 μM and 54.23 μM, respectively). Sappanchalcone reduces MMP with a significant increase in ROS levels in human colon cancer cells. Sappanchalcone triggered phosphorylation of p53, which is involved in the activation of caspases and increased expression of Bax in HCT116 cells[1].
References	[1]. Seo HW, et al. Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. Chem Biol Interact. 2020;327:109185.

Density	1.4±0.1 g/cm3
Boiling Point	581.7±50.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₄O₅
Molecular Weight	286.279
Flash Point	221.0±23.6 °C
Exact Mass	286.084137
PSA	86.99000
LogP	2.51
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.684

Hazard Codes	Xi
HS Code	2914509090

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%