N-{(4R)-4-(4-Methoxyphenyl)-3-[2-(4-methoxyphenyl)ethyl]-2-oxo-1- imidazolidinyl}methanesulfonamide
Modify Date: 2024-09-15 11:42:48
![N-{(4R)-4-(4-Methoxyphenyl)-3-[2-(4-methoxyphenyl)ethyl]-2-oxo-1- imidazolidinyl}methanesulfonamide Structure](https://www.chemsrc.com/caspic/125/1000306-34-2.png)
N-{(4R)-4-(4-Methoxyphenyl)-3-[2-(4-methoxyphenyl)ethyl]-2-oxo-1- imidazolidinyl}methanesulfonamide structure
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Common Name | N-{(4R)-4-(4-Methoxyphenyl)-3-[2-(4-methoxyphenyl)ethyl]-2-oxo-1- imidazolidinyl}methanesulfonamide | ||
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| CAS Number | 1000306-34-2 | Molecular Weight | 419.49500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H25N3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of N-{(4R)-4-(4-Methoxyphenyl)-3-[2-(4-methoxyphenyl)ethyl]-2-oxo-1- imidazolidinyl}methanesulfonamideKVI-020 is an orally active, potent and selective blocker of the atrial potassium channel Kv1.5, with an IC50 of 480 nM. KVI-020 can inhibits hERG, with an IC50 of 15100 nM. KVI-020 is a potent antiarrhythmic agent, and can be used for atrial fibrillation (AF) research[1]. |
| Name | N-{(4R)-4-(4-Methoxyphenyl)-3-[2-(4-methoxyphenyl)ethyl]-2-oxo-1- imidazolidinyl}methanesulfonamide |
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| Description | KVI-020 is an orally active, potent and selective blocker of the atrial potassium channel Kv1.5, with an IC50 of 480 nM. KVI-020 can inhibits hERG, with an IC50 of 15100 nM. KVI-020 is a potent antiarrhythmic agent, and can be used for atrial fibrillation (AF) research[1]. |
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| Related Catalog | |
| Target |
IC50: 480 ± 44 nM (Kv1.5), 15100 nM (hERG)[1] |
| References |
| Molecular Formula | C20H25N3O5S |
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| Molecular Weight | 419.49500 |
| Exact Mass | 419.15100 |
| PSA | 96.56000 |
| LogP | 3.53690 |