Potassium tetrachloroplatinate(II)

Modify Date: 2024-01-02 14:55:48

Potassium tetrachloroplatinate(II) structure	Common Name	Potassium tetrachloroplatinate(II)
	CAS Number	10025-99-7	Molecular Weight	415.08700
	Density	3.38 g/mL at 25 °C(lit.)	Boiling Point	N/A
	Molecular Formula	Cl₄K₂Pt	Melting Point	250°C
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS05, GHS06, GHS08	Signal Word	Danger

Name	dipotassium tetrachloroplatinate
Synonym	More Synonyms

Density	3.38 g/mL at 25 °C(lit.)
Melting Point	250°C
Molecular Formula	Cl₄K₂Pt
Molecular Weight	415.08700
Exact Mass	412.76800
LogP	2.75550
Stability	Stable. Incompatible with acids, strong oxidizing agents.
Water Solubility	10 g/L (20 ºC)

Potassium tetrachloroplatinate(II) MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP1850000

CHEMICAL NAME :: Platinate(2-), tetrachloro-, dipotassium

CAS REGISTRY NUMBER :: 10025-99-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 34

MOLECULAR FORMULA :: Cl4-Pt.2K

MOLECULAR WEIGHT :: 415.09

WISWESSER LINE NOTATION :: KA2 PT-G4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Cardiac - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 8571 ug/kg

TOXIC EFFECTS :: Gastrointestinal - gastritis Kidney, Ureter, Bladder - renal function tests depressed Blood - eosinophilia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intradermal

SPECIES OBSERVED :: Human

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Skin and Appendages - primary irritation (after topical exposure) Skin and Appendages - corrosive (after topical exposure)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 65 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1463,1980 *** REVIEWS *** ACGIH TLV-TWA 0.002 mg(Pt)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.002 mg(Pt)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,213,1971 OSHA PEL (Gen Indu):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.002 mg(Pt)/m3 (dust) JAN 1993 OEL-AUSTRALIA:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-BELGIUM:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-DENMARK:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-FINLAND:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-GERMANY:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-HUNGARY:STEL 0.002 mg(Pt)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

Symbol	GHS05, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H315-H317-H318-H334
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25;R38;R41;R42/43
Safety Phrases	S22-S26-S36/37/39-S45
RIDADR	UN 3288 6.1/PG 3
WGK Germany	1
RTECS	TP1850000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	2922509090

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HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synthesis of a platinum(II) complex with 2-(4-methoxy-phenyl) imidazo [4,5-f]-[1,10] phenanthrolin and study of its antitumor activity.

Eur. J. Med. Chem. 89 , 77-87, (2014)

A new platinum(II) complex of [Pt(II)(L) (pn)]Cl·2H2O (1) (pn = 1,3-propanediamine) with 2-(4-methoxy-phenyl)imidazo [4,5-f]-[1,10]phenanthrolin (H-L) was synthesized and characterized. In complex 1, ...

Monofunctional Platinum-containing Pyridine-based Ligand Acts Synergistically in Combination with the Phytochemicals Curcumin and Quercetin in Human Ovarian Tumour Models.

Anticancer Res. 35 , 2783-94, (2015)

With the idea that platinum compounds that bind with DNA differently than cisplatin may be better-able to overcome platinum resistance in ovarian tumor, the monofunctional platinum complex tris(imidaz...

Platinum complexes and pyruvate kinase activity.

Gen. Physiol. Biophys. 17(1) , 25-36, (1998)

The interaction of platinum complexes with bovine heart pyruvate kinase (PK) was studied by absorption, CD, fluorescence spectroscopy and enzymic activity test. Our results showed that activity of PK ...

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MFCD00011378

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China
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China
Product Name: Potassium tetrachloroplatinate(II)
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Potassium tetrachloroplatinate(II)

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