A7132

Modify Date: 2024-01-15 05:46:28

A7132 Structure
A7132 structure
Common Name A7132
CAS Number 100490-21-9 Molecular Weight 386.35200
Density N/A Boiling Point N/A
Molecular Formula C19H16F2N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A7132


A7132 is an antibacterial agent. A7132 possess broad and potent antibacterial activity.

 Names

Name 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid
Synonym More Synonyms

 A7132 Biological Activity

Description A7132 is an antibacterial agent. A7132 possess broad and potent antibacterial activity.
Related Catalog
Target

Antibacterial[1]

In Vitro A7132 (Compound 31) shows great oral activity against S. aureus NCTC 10649, E. coli Juhl and P. aeruginosa 5007 with MICs of 0.25, 0.05 and 0.39 μg/mL, respectively[1].
References

[1]. Chu DT, et al. Synthesis and structure-activity relationships of new arylfluoronaphthyridine antibacterialagents. J Med Chem. 1986 Nov;29(11):2363-9.

 Chemical & Physical Properties

Molecular Formula C19H16F2N4O3
Molecular Weight 386.35200
Exact Mass 386.11900
PSA 87.46000
LogP 2.16550

 Synonyms

1-p-fluorophenyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid
6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
sarafloxacin
A7132