PIM-IN-2

Modify Date: 2024-01-25 13:56:29

PIM-IN-2 Structure
PIM-IN-2 structure
Common Name PIM-IN-2
CAS Number 1006699-45-1 Molecular Weight 338.40
Density N/A Boiling Point N/A
Molecular Formula C19H22N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PIM-IN-2


PIM-IN-2 (Pim-2) is a Pim kinases inhibitor (IC50 = 25 nM). PIM-IN-2 promotes cell survival, is antiapoptotic, and has exhibited an elevated level of expression in a variety of human tumors[1].

 Names

Name PIM-IN-2

 PIM-IN-2 Biological Activity

Description PIM-IN-2 (Pim-2) is a Pim kinases inhibitor (IC50 = 25 nM). PIM-IN-2 promotes cell survival, is antiapoptotic, and has exhibited an elevated level of expression in a variety of human tumors[1].
Related Catalog
Target

PIM2

References

[1]. Qian K, et al. Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode [J]. Journal of medicinal chemistry, 2009, 52(7): 1814-1827.  

 Chemical & Physical Properties

Molecular Formula C19H22N4O2
Molecular Weight 338.40