NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE

Modify Date: 2024-01-08 11:01:07

NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE structure	Common Name	NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE
	CAS Number	100900-19-4	Molecular Weight	679.76600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₄₅N₉O₇	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS08	Signal Word	Warning

Use of NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE

Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λex = 355 nm, λem = 430 nm)[1][2].

Name	acetic acid,benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methoxynaphthalen-2-yl)amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Synonym	More Synonyms

Description	Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λex = 355 nm, λem = 430 nm)[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	Cathepsin B
References	[1]. Büth H, et al. HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration. Eur J Cell Biol. 2004 Dec;83(11-12):781-95. [2]. van den Bos T, et al. Differences in matrix composition between calvaria and long bone in mice suggest differences in biomechanical properties and resorption: Special emphasis on collagen. Bone. 2008 Sep;43(3):459-68.

Molecular Formula	C₃₃H₄₅N₉O₇
Molecular Weight	679.76600
Exact Mass	679.34400
PSA	277.33000
LogP	6.26020

NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE MSDS(Chinese)

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H351
Precautionary Statements	P281
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn: Harmful;
Risk Phrases	40
Safety Phrases	22-36
RIDADR	NONH for all modes of transport

A simple, economical method for staining gels for cathepsin B-like activity.

Anal. Biochem. 119 , 148, (1982)

In vivo and in vitro evidence for the involvement of cysteine proteinases in bone resorption.

Biochem. Biophys. Res. Commun. 125 , 441, (1984)

The excretion of cathepsin B, a lysosomal cysteine proteinase, by parathyroid hormone-stimulated embryonic mouse calvaria in culture, correlates closely with the extent of bone resorption evaluated by...

Z-Arg-Arg 4-methoxy-|A-naphthylamide acetate salt

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Use of NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE

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