Resorcinol diglycidyl ether

Modify Date: 2024-01-02 11:25:06

Resorcinol diglycidyl ether Structure
Resorcinol diglycidyl ether structure
Common Name Resorcinol diglycidyl ether
CAS Number 101-90-6 Molecular Weight 222.237
Density 1.2±0.1 g/cm3 Boiling Point 364.3±12.0 °C at 760 mmHg
Molecular Formula C12H14O4 Melting Point 33-35°C
MSDS Chinese USA Flash Point 156.6±26.4 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Names

Name 2-[[3-(oxiran-2-ylmethoxy)phenoxy]methyl]oxirane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 364.3±12.0 °C at 760 mmHg
Melting Point 33-35°C
Molecular Formula C12H14O4
Molecular Weight 222.237
Flash Point 156.6±26.4 °C
Exact Mass 222.089203
PSA 43.52000
LogP 1.15
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.557
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility H2O: insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VH1050000
CHEMICAL NAME :
Resorcinol, diglycidyl-
CAS REGISTRY NUMBER :
101-90-6
BEILSTEIN REFERENCE NO. :
0203671
LAST UPDATED :
199710
DATA ITEMS CITED :
34
MOLECULAR FORMULA :
C12-H14-O4
MOLECULAR WEIGHT :
222.26
WISWESSER LINE NOTATION :
T3OTJ B1OR CO1- BT3OTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2570 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from duodenum
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
178 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - peritonitis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
980 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
243 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - peritonitis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1240 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5320 mg/kg/14D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13 gm/kg/13W-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10500 mg/kg/14D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
26 gm/kg/13W-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6180 mg/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25750 mg/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6700 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
51500 mg/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25750 mg/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
12875 mg/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Heritable translocation test

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
50 ug/L
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 236,933,1987 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 36,181,1985 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 36,181,1985 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83725 No. of Facilities: 193 (estimated) No. of Industries: 4 No. of Occupations: 8 No. of Employees: 2994 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83725 No. of Facilities: 28 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 1856 (estimated) No. of Female Employees: 222 (estimated)

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H302 + H312-H315-H317-H319-H341-H351-H412
Precautionary Statements P273-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes Xn:Harmful;
Risk Phrases R21/22;R36/38;R40;R43;R52/53;R68
Safety Phrases S23-S36/37-S61
RIDADR 2811
WGK Germany 2
RTECS VH1050000
Packaging Group II
Hazard Class 6.1
HS Code 2942000000

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2910900090
Summary 2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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 Synonyms

2,2'-[1,3-phenylenebis(oxymethylene)]bis-oxirane
Diglycidylresorcinol ether
1,3-bis-oxiranylmethoxy-benzene
2,2'-[Benzene-1,3-diylbis(oxymethanediyl)]dioxirane
T3OTJ B1OR CO1- BT3OTJ
1,3-Bis-(2,3-epoxy-propoxy)-benzol
1,3-Bis(2,3-epoxypropoxy)benzene
Oxirane, 2,2'-[1,3-phenylenebis(oxymethylene)]bis-
diglycidyl ether of resorcinol
1,3-BENZENDIOL BIS(2-PROPENYL)ETHER BISEPOXIDE
Benzene,m-bis(2,3-epoxypropoxy)
MFCD00078378
Diglycidyl resorcinol ether
Araldite ERE 1359
meta-bis(glycidyloxy)benzene
EINECS 202-987-5
m-bis(glycidyloxy)benzene
2,2'-[1,3-Phenylenebis(oxymethylene)]dioxirane
DGRE
1,3-Bis(oxiran-2-ylmethoxy)benzene
diglicidyl resorcinol ether
1,3-Bis(glycidyloxy)benzene
RDGE
Resorcinyl diglycidyl ether
Resorcinol diglycidyl ether
1,3-DIGLYCIDYLOXYBENZENE