Curvularin structure
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Common Name | Curvularin | ||
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CAS Number | 10140-70-2 | Molecular Weight | 292.32700 | |
Density | 1.2g/cm3 | Boiling Point | 557ºC at 760mmHg | |
Molecular Formula | C16H20O5 | Melting Point | 205-207 °C | |
MSDS | Chinese USA | Flash Point | 207.9ºC | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of CurvularinCurvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC50 of 9.5 µM[1][2]. |
Name | 2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (-) |
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Synonym | More Synonyms |
Description | Curvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC50 of 9.5 µM[1][2]. |
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Related Catalog | |
Target |
IC50: 9.5 µM (iNOS)[2]. |
References |
Density | 1.2g/cm3 |
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Boiling Point | 557ºC at 760mmHg |
Melting Point | 205-207 °C |
Molecular Formula | C16H20O5 |
Molecular Weight | 292.32700 |
Flash Point | 207.9ºC |
Exact Mass | 292.13100 |
PSA | 83.83000 |
LogP | 2.71880 |
Vapour Pressure | 5.18E-13mmHg at 25°C |
Index of Refraction | 1.54 |
Sulfur-containing cytotoxic curvularin macrolides from Penicillium sumatrense MA-92, a fungus obtained from the rhizosphere of the mangrove Lumnitzera racemosa.
J. Nat. Prod. 76(11) , 2145-9, (2013) Sumalarins A-C (1-3), the new and rare examples of sulfur-containing curvularin derivatives, along with three known analogues (4-6), were isolated and identified from the cytotoxic extract of Penicill... |
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Metabolite production by differentUlocladiumspecies
Int. J. Food Microbiol. 126(1-2) , 172-9, (2008) Ulocladium, which is phylogenetically related to Alternaria, contains species that are food spoilers and plant pathogens, but also species that have potential as enzyme producers and bio-control agent... |
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[Molecular basis of probes for cytoskeletal proteins].
Tanpakushitsu Kakusan Koso. 38(11) , 1730-41, (1993)
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curvularin |