Diclazuril

Modify Date: 2024-01-02 17:48:38

Diclazuril Structure
Diclazuril structure
Common Name Diclazuril
CAS Number 101831-37-2 Molecular Weight 407.638
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C17H9Cl3N4O2 Melting Point 548ºC
MSDS Chinese USA Flash Point N/A

 Use of Diclazuril


Diclazuril is an anti-coccidial drug. Target: AntiparasiticDiclazuril is a coccidiostat, the lambs treated with diclazuril showed an intense, persistent oocyst excretion, with average levels of 97.54 opg, considerably higher than those recorded in the animals treated with toltrazuril (p < 0.05) [1]. Diclazuril is effective against E. maxima later in its life cycle, subclinical intestinal lesions may be present for a short time after infection. Diclazuril was shown in studies to reduce lesion scores and improve performance and health of birds challenged with E. maxima [2].

 Names

Name Diclazuril
Synonym More Synonyms

 Diclazuril Biological Activity

Description Diclazuril is an anti-coccidial drug. Target: AntiparasiticDiclazuril is a coccidiostat, the lambs treated with diclazuril showed an intense, persistent oocyst excretion, with average levels of 97.54 opg, considerably higher than those recorded in the animals treated with toltrazuril (p < 0.05) [1]. Diclazuril is effective against E. maxima later in its life cycle, subclinical intestinal lesions may be present for a short time after infection. Diclazuril was shown in studies to reduce lesion scores and improve performance and health of birds challenged with E. maxima [2].
Related Catalog
References

[1]. Diaferia, M., et al., Efficacy of toltrazuril 5 % suspension (Baycox(R), Bayer) and diclazuril (Vecoxan(R), Janssen-Cilag) in the control of Eimeria spp. in lambs. Parasitol Res, 2013. 112 Suppl 1: p. 163-8.

[2]. http://www.huvepharma.com/products/view/190

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Melting Point 548ºC
Molecular Formula C17H9Cl3N4O2
Molecular Weight 407.638
Exact Mass 405.979095
PSA 91.54000
LogP 2.44
Index of Refraction 1.702
Storage condition 0-6°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles26

More Articles
Increased level of Eimeria sensitivity to diclazuril after using a live coccidial vaccine.

Avian Dis. 50(3) , 321-4, (2006)

Anticoccidial vaccine and an anticoccidial drug rotation program were compared to determine which program was more effective in producing coccidia populations sensitive of 1 ppm diclazuril. The study ...

Comparison of three adjuvants used to produce polyclonal antibodies to veterinary drugs.

Vet. Immunol. Immunopathol. 122(1-2) , 25-34, (2008)

Two commercially available adjuvants, Gerbu LQ 3000 and Montanide ISA 50V, were assessed as potential replacements for Freund's adjuvant by evaluating their efficacy in the production of polyclonal an...

Determination of diclazuril, toltrazuril and its two metabolites in poultry tissues and eggs by gel permeation chromatography-liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(20) , 1757-63, (2011)

A new procedure has been described for the extraction of diclazuril (DIZ), toltrazuril (TOZ) and its two main metabolites toltrazuril sulphoxide (TZSO) and toltrazuril sulphone (TZS) from poultry tiss...

 Synonyms

Vecoxan
Qiujia
MFCD00867203
CLINACOX
Nuoqiu
DICLAZUTIL
clinazox
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