Protosappanin B structure
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Common Name | Protosappanin B | ||
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CAS Number | 102036-29-3 | Molecular Weight | 304.29 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 655.5±55.0 °C at 760 mmHg | |
Molecular Formula | C16H16O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 350.2±31.5 °C |
Use of Protosappanin BProtosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2]. |
Name | Protosappanin B |
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Synonym | More Synonyms |
Description | Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2]. |
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Related Catalog | |
Target |
Apoptosis[2] |
In Vitro | Protosappanin B (12.5, 25, 50, 100, 200 µg/mL, 48 hours) dose-dependently inhibits tumor cells, with IC50s of 21.32 µg/mL, 26.73 µg/mL, and 76.53 µg/mL for SW-480, HCT-116, and BTT cells, respectively[1]. Cell Viability Assay[1] Cell Line: CT-116, SW-480, and BTT Cells Concentration: 12.5, 25, 50, 100, 200 µg/mL Incubation Time: 48 hours Result: Dose-dependently inhibited tumor cells after 48 hours of treatment. |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 655.5±55.0 °C at 760 mmHg |
Molecular Formula | C16H16O6 |
Molecular Weight | 304.29 |
Flash Point | 350.2±31.5 °C |
Exact Mass | 304.094696 |
PSA | 110.38000 |
LogP | 1.13 |
Vapour Pressure | 0.0±2.1 mmHg at 25°C |
Index of Refraction | 1.700 |
Storage condition | 2~8℃ |
Hazard Codes | Xi |
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~% Protosappanin B CAS#:102036-29-3 |
Literature: Chemical and Pharmaceutical Bulletin, , vol. 38, # 6 p. 1490 - 1494 |
~% Protosappanin B CAS#:102036-29-3 |
Literature: Chemical & Pharmaceutical Bulletin, , vol. 35, # 7 p. 3002 - 3005 |
Precursor 1 | |
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DownStream 0 |
(7S)-7-(Hydroxymethyl)-7,8-dihydro-6H-dibenzo[b,d]oxocine-3,7,10,11-tetrol |
6H-Dibenz[b,d]oxocin-3,7,10,11-tetrol, 7,8-dihydro-7-(hydroxymethyl)-, (7S)- |