baquiloprim

Modify Date: 2024-01-04 19:37:32

baquiloprim Structure
baquiloprim structure
Common Name baquiloprim
CAS Number 102280-35-3 Molecular Weight 308.381
Density 1.3±0.1 g/cm3 Boiling Point 567.9±60.0 °C at 760 mmHg
Molecular Formula C17H20N6 Melting Point N/A
MSDS Chinese USA Flash Point 297.2±32.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of baquiloprim


Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2].

 Names

Name baquiloprim
Synonym More Synonyms

 baquiloprim Biological Activity

Description Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2].
Related Catalog
References

[1]. Lewicki J, et, al. Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats. Res Vet Sci. 1995 May;58(3):268-71.

[2]. White DG, et, al. Comparison of danofloxacin with baquiloprim/sulphadimidine for the treatment of experimentally induced Escherichia coli diarrhoea in calves. Vet Rec. 1998 Sep 5;143(10):273-6.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 567.9±60.0 °C at 760 mmHg
Molecular Formula C17H20N6
Molecular Weight 308.381
Flash Point 297.2±32.9 °C
Exact Mass 308.174957
PSA 93.95000
LogP 2.32
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.719

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xn
Risk Phrases 22-36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
RTECS UV8142576

 Articles7

More Articles
Eimeria alabamensis coccidiosis in grazing calves: control by a long-acting baquiloprim/sulphadimidine bolus.

Appl. Parasitol. 37(3) , 168-76, (1996)

The excretion of Eimeria oocysts, the faecal dry matter and the weight gain of three groups of 12 calves, were compared during their first 20 days of grazing on a pasture known to have been contaminat...

Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats.

Res. Vet. Sci. 58(3) , 268-71, (1995)

The pharmacokinetics of baquiloprim at a dose of 8 mg kg-1 bodyweight were determined after its intravenous and intra-ruminal administration to seven healthy female dwarf goats. After intravenous inje...

Prevention of Eimeria alabamensis coccidiosis by a long-acting baquiloprim/sulphadimidine bolus.

Vet. Parasitol. 74(2-4) , 143-52, (1998)

Twelve calves aged 6-10 months, and 12 calves aged 10-16 months were turned out onto a permanent pasture known to have been contaminated with oocysts of Eimeria alabamensis during the previous year. T...

 Synonyms

5-{[8-(Dimethylamino)-7-methyl-5-quinolinyl]methyl}-2,4-pyrimidinediamine
baquiloprim
2,4-Pyrimidinediamine, 5-[[8-(dimethylamino)-7-methyl-5-quinolinyl]methyl]-
5-((2,4-Diamino-5-pyrimidinyl)methyl)-8-(dimethylamino)-7-methylquinoline
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