LY2452473

Modify Date: 2024-01-11 22:04:32

LY2452473 Structure
LY2452473 structure
Common Name LY2452473
CAS Number 1029692-15-6 Molecular Weight 374.43600
Density N/A Boiling Point N/A
Molecular Formula C22H22N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY2452473


LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM).

 Names

Name propan-2-yl N-[(2S)-7-cyano-4-(pyridin-2-ylmethyl)-2,3-dihydro-1H-cyclopenta[b]indol-2-yl]carbamate
Synonym More Synonyms

 LY2452473 Biological Activity

Description LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM).
Related Catalog
Target

Androgen receptor[1]

In Vivo LY2452473 is a selective androgen receptor modulator being developed for the treatment of disorders related to hypogonadism. LY2452473 is absorbed rapidly (time to reach maximum plasma concentration for both LY2452473 and total radioactivity is 2-3 h) and cleared slowly (plasma terminal t1/2 of 27 h for LY2452473 and 51 h for the total radioactivity)[1].
References

[1]. Yi P, et al. Disposition and metabolism of LY2452473, a selective androgen receptor modulator, in humans. Drug Metab Dispos. 2012 Dec;40(12):2354-64.

 Chemical & Physical Properties

Molecular Formula C22H22N4O2
Molecular Weight 374.43600
Exact Mass 374.17400
PSA 83.43000
LogP 3.76248
Storage condition 2-8℃

 Synonyms

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LY2452473
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Price: ¥1210/10 mM * 1 mL in DMSO

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