SRI 37892
Modify Date: 2024-04-07 12:42:27
SRI 37892 structure
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Common Name | SRI 37892 | ||
|---|---|---|---|---|
| CAS Number | 1030769-75-5 | Molecular Weight | 465.531 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H19N5O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SRI 37892SRI 37892 (SRI37892) is a novel potent, small molecule Frizzled 7 (Fzd 7) inhibitor with IC50 of 0.66 uM in Wnt/β-catenin assay; also displays potent activity against Wnt/β-catenin signaling in LRP6-expressing HEK293 cells with IC50 of 0.78 uM, demonstrates potent activity against breast cancer HS578T and BT549 cell proliferation with IC50 of 2.2 and 1.9 uM, respectively; targets Fzd7 transmembrane domain (TMD) and bolcks Wnt/Fzd7 signaling. |
| Name | SRI 37892 |
|---|
| Description | SRI 37892 (SRI37892) is a novel potent, small molecule Frizzled 7 (Fzd 7) inhibitor with IC50 of 0.66 uM in Wnt/β-catenin assay; also displays potent activity against Wnt/β-catenin signaling in LRP6-expressing HEK293 cells with IC50 of 0.78 uM, demonstrates potent activity against breast cancer HS578T and BT549 cell proliferation with IC50 of 2.2 and 1.9 uM, respectively; targets Fzd7 transmembrane domain (TMD) and bolcks Wnt/Fzd7 signaling. |
|---|---|
| References | References 1. Zhang W, et al. Oncotarget. 2017 Sep 6;8(53):91459-91470. View Related Products by Target Frizzled |
| Molecular Formula | C26H19N5O2S |
|---|---|
| Molecular Weight | 465.531 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: SRI 37892
- Price: Negotiable
- Purity: 98.92%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: SRI 37892
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: SRI 37892
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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