4'-Piperidinoacetophenone

Modify Date: 2024-01-11 14:31:13

4'-Piperidinoacetophenone Structure
4'-Piperidinoacetophenone structure
Common Name 4'-Piperidinoacetophenone
CAS Number 10342-85-5 Molecular Weight 203.28000
Density 1.052g/cm3 Boiling Point 357.8ºC at 760 mmHg
Molecular Formula C13H17NO Melting Point 85-87 °C(lit.)
MSDS Chinese USA Flash Point 140.2ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4'-Piperidinoacetophenone


4′-Piperidinoacetophenone undergoes Claisen-Schmidt condensation with substituted benzaldehydes using NaOH-Al2O3 by microwave irradiation to give chalcones. It has antimycobacterial activity.

 Names

Name 1-(4-piperidin-1-ylphenyl)ethanone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.052g/cm3
Boiling Point 357.8ºC at 760 mmHg
Melting Point 85-87 °C(lit.)
Molecular Formula C13H17NO
Molecular Weight 203.28000
Flash Point 140.2ºC
Exact Mass 203.13100
PSA 20.31000
LogP 2.94450
Vapour Pressure 2.66E-05mmHg at 25°C
Index of Refraction 1.545

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles3

More Articles
Acetophenones with selective antimycobacterial activity.

Lett. Appl. Microbiol. 40 , 212-217, (2005)

Mycobacteria are a serious cause of infections in humans, with limited treatment options, as no new antibiotics have been developed against mycobacteria since the 1960s. In this study, the antimycobac...

Sensitive determination of pethidine in body fluids by gas chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 792(1) , 117-21, (2003)

We have presented a simple and sensitive method for determining pethidine, a narcotic analgesic drug in body fluids by gas chromatography-tandem mass spectrometry (GC-MS/MS). Pethidine and 4'-piperidi...

Microwave enhanced Claisen-Schmidt condensation: A green route to chalcones. Singh JP, et al.

Indian J. Chem. B 51(11) , 1623, (2012)

 Synonyms

1-(4-piperidin-1-yl-phenyl)ethanone
1-(4-acetylphenyl)piperidine
4-piperidino acetophenone
MFCD00006481
EINECS 233-746-2
1-[4-(1-piperidinyl)phenyl]ethanone
1-acetyl-4-piperidylbenzene
p-(piperidino)acetophenone
Ethanone,1-(4-(1-piperidinyl)phenyl)
(4-piperidinophenyl) methyl ketone
p-(1-Piperidino)acetophenone
4'-Piperidinoacetophenone
1-[4-(Piperidin-1-yl)phenyl]ethan-1-one
4-Piperidinoacetophenone
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