Tetrapeptide-30

Modify Date: 2024-01-03 23:54:39

Tetrapeptide-30 Structure
Tetrapeptide-30 structure
Common Name Tetrapeptide-30
CAS Number 1036207-61-0 Molecular Weight 500.596
Density 1.256±0.06 g/cm3(Predicted) Boiling Point 931.5±65.0 °C(Predicted)
Molecular Formula C22H40N6O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tetrapeptide-30


Tetrapeptide-30 is a skin-brightening peptide consisting of four amino acids. Tetrapeptide-30 can act as a tyrosinase inhibitor, lightening hyperpigmentation and evening out skin tone by reducing the amount of tyrosinase and inhibiting melanocyte activation[1].

 Names

Name Tetrapeptide-30

 Tetrapeptide-30 Biological Activity

Description Tetrapeptide-30 is a skin-brightening peptide consisting of four amino acids. Tetrapeptide-30 can act as a tyrosinase inhibitor, lightening hyperpigmentation and evening out skin tone by reducing the amount of tyrosinase and inhibiting melanocyte activation[1].
Related Catalog
In Vitro Tetrapeptide-30 (0-10 μg/mL, 24 h) can effectively reduce UVB-induced gene expression of IL-6, TNF-α and POMC (proopiomelanocorticotropin), and also decreased IL-8 gene expression in a dose-dependent manner[1]. Tetrapeptide-30 (PKEK) is highly hydrophilic and has good skin penetration in microemulsion[2].
References

[1]. Alessandra Marini, et al. Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects. Exp Dermatol. 2012 Feb;21(2):140-6.

[2]. Reinhard H H Neubert, et al. Dermal peptide delivery using enhancer moleculs and colloidal carrier systems. Part II: Tetrapeptide PKEK. Eur J Pharm Biopharm. 2018 Mar;124:28-33.

 Chemical & Physical Properties

Density 1.256±0.06 g/cm3(Predicted)
Boiling Point 931.5±65.0 °C(Predicted)
Molecular Formula C22H40N6O7
Molecular Weight 500.596