Benralizumab

Modify Date: 2024-01-05 17:17:39

Benralizumab Structure
Benralizumab structure
Common Name Benralizumab
CAS Number 1044511-01-4 Molecular Weight 146054.0
Density N/A Boiling Point N/A
Molecular Formula C6492H10060N1724O2028S42 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benralizumab


Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used to treat severe eosinophilic asthma[1].

 Names

Name Benralizumab

 Benralizumab Biological Activity

Description Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used to treat severe eosinophilic asthma[1].
Related Catalog
Target

IL-5Rα[1]

References

[1]. Menzies-Gow A, et al. Corticosteroid tapering with benralizumab treatment for eosinophilic asthma: PONENTE Trial. ERJ Open Res. 2019 Sep 25;5(3). pii: 00009-2019.

 Chemical & Physical Properties

Molecular Formula C6492H10060N1724O2028S42
Molecular Weight 146054.0