5-Ethylphenazin-5-ium ethyl sulfate

Modify Date: 2024-01-02 16:10:15

5-Ethylphenazin-5-ium ethyl sulfate Structure
5-Ethylphenazin-5-ium ethyl sulfate structure
Common Name 5-Ethylphenazin-5-ium ethyl sulfate
CAS Number 10510-77-7 Molecular Weight 334.390
Density N/A Boiling Point N/A
Molecular Formula C16H18N2O4S Melting Point 190℃
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of 5-Ethylphenazin-5-ium ethyl sulfate


Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid[1][2][3].

 Names

Name Phenazine ethosulfate
Synonym More Synonyms

 5-Ethylphenazin-5-ium ethyl sulfate Biological Activity

Description Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid[1][2][3].
Related Catalog
References

[1]. R Ghosh, et al. Phenazine ethosulfate as a preferred electron acceptor to phenazine methosulfate in dye-linked enzyme assays. Anal Biochem. 1979 Oct 15;99(1):112-7.

[2]. O.A.Ryazanova, et al. pH-Induced changes in electronic absorption and fluorescence spectra of phenazine derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2007 Apr;66(4-5):849-59.

[3]. Jessica H van Wonderen, et al. The nitric oxide reductase activity of cytochrome c nitrite reductase from Escherichia coli. J Biol Chem. 2008 Apr 11;283(15):9587-94.

 Chemical & Physical Properties

Melting Point 190℃
Molecular Formula C16H18N2O4S
Molecular Weight 334.390
Exact Mass 334.098724
PSA 91.58000
LogP 3.25930

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SG1635000
CHEMICAL NAME :
Phenazinium, 5-ethyl-, ethylsulfate
CAS REGISTRY NUMBER :
10510-77-7
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H13-N2.C2-H5-O4-S
MOLECULAR WEIGHT :
334.42
WISWESSER LINE NOTATION :
T C666 CK INJ C2 &WSO&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,203,1976

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases S26;S36
RIDADR NONH for all modes of transport
RTECS SG1635000
HS Code 2933990090

 Synthetic Route

~%

5-Ethylphenazin-5-ium ethyl sulfate Structure

5-Ethylphenazin...

CAS#:10510-77-7

Literature: Journal of the Chemical Society, , p. 1704,1710

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles42

More Articles
Organophosphate pesticides-induced changes in the redox status of rat tissues and protective effects of antioxidant vitamins.

Environ. Toxicol. 30(4) , 472-82, (2015)

Organophosphates (OPs) pesticides are among the most toxic synthetic chemicals purposefully added in the environment. The common use of OP insecticides in public health and agriculture results in an e...

Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice.

Int. J. Hematol. 102 , 327-34, (2015)

Indoleamine 2,3-dioxygenase (IDO) catalyzes the rate-limiting step in the metabolism of tryptophan along the kynurenine pathway. In tumors, increased IDO activity inhibits proliferation and induces ap...

The anti-lymphoma activity of APO866, an inhibitor of nicotinamide adenine dinucleotide biosynthesis, is potentialized when used in combination with anti-CD20 antibody.

Leuk. Lymphoma 55(9) , 2141-50, (2014)

APO866 is an inhibitor of nicotinamide adenine dinucleotide (NAD) biosynthesis that exhibits potent anti-lymphoma activity. Rituximab (RTX), an anti-CD20 antibody, kills lymphoma cells by direct apopt...

 Synonyms

EINECS 234-044-9
MFCD00050286
5-Ethylphenazin-5-ium ethyl sulfate
5-ethylphenazin-5-ium,ethyl sulfate