5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite

Modify Date: 2024-01-08 19:01:40

5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite Structure
5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite structure
Common Name 5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite
CAS Number 105931-57-5 Molecular Weight 847.93400
Density N/A Boiling Point N/A
Molecular Formula C47H54N5O8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite


DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding[1].

 Names

Name [5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-deoxy-N4-benzoyl-5-methylcytidin-3'-O-yl]-2-cyanoethyl-N,N-diisopropylphosphoramidite
Synonym More Synonyms

  Biological Activity

Description DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding[1].
Related Catalog
References

[1]. Irina V Astakhova, et al. LNA for optimization of fluorescent oligonucleotide probes: improved spectral properties and target binding. Bioconjug Chem. 2011 Apr 20;22(4):533-9.

 Chemical & Physical Properties

Molecular Formula C47H54N5O8P
Molecular Weight 847.93400
Exact Mass 847.37100
PSA 159.99000
LogP 8.85158
Storage condition -20℃

 Synonyms

n4-benzoyl-2'-deoxy-5'-o-dmt-5-methylcytidine 3'-ce phosphoramidite
n4-benzoyl-2'-deoxy-5'-o-[bis(4-methoxyphenyl)phenylmethyl]-5-methylcytidine 3'-ce phosphoramidite
5'-o-(4,4'-dimethoxytrityl)-5-methyl-n4-benzoyl-2'-deoxycytidine-3'-(2-cyanoethyl-n,n-diisopropyl)phosphoramidite