Rufloxacin (hydrochloride)

Modify Date: 2024-01-09 17:40:18

Rufloxacin (hydrochloride) structure	Common Name	Rufloxacin (hydrochloride)
	CAS Number	106017-08-7	Molecular Weight	399.86700
	Density	N/A	Boiling Point	574.6ºC at 760mmHg
	Molecular Formula	C₁₇H₁₉ClFN₃O₃S	Melting Point	322-324ºC
	MSDS	N/A	Flash Point	301.3ºC

Use of Rufloxacin (hydrochloride)

Rufloxacin hydrochloride (MF-934 hydrochloride) is a fluoroquinolone antibacterial, inhibits B-cell differentiation in human mononuclear cells, inhibits Topo.

Name	rufloxacin hydrochloride
Synonym	More Synonyms

Description	Rufloxacin hydrochloride (MF-934 hydrochloride) is a fluoroquinolone antibacterial, inhibits B-cell differentiation in human mononuclear cells, inhibits Topo.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection

Boiling Point	574.6ºC at 760mmHg
Melting Point	322-324ºC
Molecular Formula	C₁₇H₁₉ClFN₃O₃S
Molecular Weight	399.86700
Flash Point	301.3ºC
Exact Mass	399.08200
PSA	91.08000
LogP	2.50120
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU8174500

CHEMICAL NAME :: 7H-Pyrido(1,2,3-de)(1,4)benzothiazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-10-(4-methyl-1- piperazinyl)-7-oxo-, monohydrochloride

CAS REGISTRY NUMBER :: 106017-08-7

LAST UPDATED :: 198709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C17-H18-F-N3-O3-S.Cl-H

MOLECULAR WEIGHT :: 399.90

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 501 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 30,465,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 285 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 30,465,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 224 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 30,465,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 660 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 30,465,1987

HS Code	2942000000

ethyl 2,3,5-tri...

CAS#:108860-30-6

N,N-Dimethylfor...

CAS#:4637-24-5

2-Aminoethanethiol

CAS#:60-23-1

~71%

Rufloxacin (hyd...

CAS#:106017-08-7

Literature: Mediolanum Farmaceutici S.p.A. Patent: US5221741 A1, 1993 ;

N/A

CAS#:138944-13-5

~88%

Rufloxacin (hyd...

CAS#:106017-08-7

Literature: Cecchetti; Fravolini; Schiaffella Synthetic Communications, 1991 , vol. 21, # 22 p. 2301 - 2308

ethyl 2,3,5-tri...

CAS#:108860-30-6

Rufloxacin (hyd...

CAS#:106017-08-7

Literature: Synthetic Communications, , vol. 21, # 22 p. 2301 - 2308

ethyl 2-[2,3,5-...

CAS#:113933-55-4

Rufloxacin (hyd...

CAS#:106017-08-7

Literature: Synthetic Communications, , vol. 21, # 22 p. 2301 - 2308

N/A

CAS#:138944-12-4

Rufloxacin (hyd...

CAS#:106017-08-7

Literature: Synthetic Communications, , vol. 21, # 22 p. 2301 - 2308

Precursor 4
CAS#:108860-30-6 ethyl 2,3,5-tri... CAS#:4637-24-5 N,N-Dimethylfor... CAS#:60-23-1 2-Aminoethanethiol CAS#:113933-55-4 ethyl 2-[2,3,5-...
DownStream 0

HS Code	2942000000

7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylicacid,9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-,hydrochloride(1:1)

MF-934

MFCD00912283

9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acid hydrochloride

7H-Pyrido(1,2,3-de)(1,4)benzothiazine-6-carboxylic acid,2,3-dihydro-9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-,monohydrochloride

Rufloxacin (hydrochloride)

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China
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China
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China
Product Name: rufloxacin hydrochloride
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
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Rufloxacin (hydrochloride)

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