1V209
Modify Date: 2024-01-20 11:53:47
1V209 structure
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Common Name | 1V209 | ||
|---|---|---|---|---|
| CAS Number | 1062444-54-5 | Molecular Weight | 359.34 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H17N5O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 1V2091V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects. 1V209 can be conjugated with various polysaccharides to improve its water solubility, and enhance its efficacy, and maintain low toxicity[1][2]. |
| Name | 1V209 |
|---|
| Description | 1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects. 1V209 can be conjugated with various polysaccharides to improve its water solubility, and enhance its efficacy, and maintain low toxicity[1][2]. |
|---|---|
| Related Catalog | |
| Target |
TLR7 |
| In Vitro | 1V209 (0.1-10 μM) treatment significantly stimulates TNFα production in RAW246.7 cells[1]. 1V209 (18 hours) treatment increases IL-6 production comparain bone marrow derived dendritic cells[1]. |
| In Vivo | The intravenous (IV) administration of the formulation to mice bearing 4T1 breast cancer tumors results in nanoparticle accumulation in tumors, reduction in primary tumor growth, and inhibition of lung metastases, as compared to saline-treated animals. Mice administered 1V209 experience significantly increases plasma levels of proinflammatory cytokines IL-6, IP-10, and MCP-1 at 2 h following IV administration[1]. |
| References |
| Molecular Formula | C16H17N5O5 |
|---|---|
| Molecular Weight | 359.34 |
| Hazard Codes | Xi |
|---|
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 1V209
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: 1V209(TLR7 agonist T7)
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: 1V209(TLR7 agonist T7)
- Price: $600.0/100mg $1100.0/250mg $2200.0/1g
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
Get all suppliers and price by the below link:
Price: ￥580/1 mg
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