1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone

Modify Date: 2024-01-02 13:36:00

1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone structure	Common Name	1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone
	CAS Number	1063-77-0	Molecular Weight	514.564
	Density	1.3±0.1 g/cm3	Boiling Point	657.7±55.0 °C at 760 mmHg
	Molecular Formula	C₂₈H₃₄O₉	Melting Point	278-279°
	MSDS	Chinese USA	Flash Point	351.6±31.5 °C

Use of 1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone

Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2].

Name	Nomilin
Synonym	More Synonyms

Description	Nomilin is a limonoid compound obtained from the extracts of citrus fruits. Nomilin is an anti-obesity and anti-hyperglycemic agent [1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Nomilin treatment significantly mitigated cell death and decreased lactate dehydrogenase (LDH) release and ROS production in SH-SY5Y cells induced by oxygen-glucose deprivation (OGD), which was almost abolished by Nrf2 knockdown[1].
In Vivo	Nomilin attenuated blood-brain barrier (BBB) disruption in MCAO rats, which might be associated with alleviating the loss of tight junction proteins, including ZO-1 and occludin-5[1].
References	[1]. Shi YS, et al. Nomilin protects against cerebral ischemia-reperfusion induced neurological deficits and blood-brain barrier disruption via the Nrf2 pathway. Food Funct. 2019 Sep 1;10(9):5323-5332. [2]. Sato R, et al. Nomilin as an anti-obesity and anti-hyperglycemic agent. Vitam Horm. 2013;91:425-39.

Density	1.3±0.1 g/cm3
Boiling Point	657.7±55.0 °C at 760 mmHg
Melting Point	278-279°
Molecular Formula	C₂₈H₃₄O₉
Molecular Weight	514.564
Flash Point	351.6±31.5 °C
Exact Mass	514.220276
PSA	121.64000
LogP	2.47
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.575

MSDS(Chinese)

Hazard Codes	Xi
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

Comparative metabolic and transcriptional analysis of a doubled diploid and its diploid citrus rootstock (C. junos cv. Ziyang xiangcheng) suggests its potential value for stress resistance improvement.

BMC Plant Biol. 15 , 89, (2015)

Polyploidy has often been considered to confer plants a better adaptation to environmental stresses. Tetraploid citrus rootstocks are expected to have stronger stress tolerance than diploid. Plenty of...

Development of delayed bitterness and effect of harvest date in stored juice from two complex citrus hybrids.

J. Sci. Food Agric. 96 , 422-9, (2015)

Mandarins and mandarin hybrids have excellent flavor and color attributes, making them good candidates for consumption as fresh fruit. When processed into juice, however, they are less palatable, as t...

Evaluation of Physiological Activities of the Citron (Citrus junos Sieb. ex TANAKA) Seed Extracts.

Prev. Nutr. Food Sci. 18 , 196-202, (2014)

Citron seed extracts (CSEs) were made using distilled water (CSEW), ethanol (CSEE), and n-hexane (CSEH), to measure the total polyphenol contents, DPPH and ABTS radical scavenging activities, and anti...

fromcitrusseeds

1-(Acetyloxy)-1,2-dihydroobacunoic Acid e-Lactone

Oxireno[4',5']pyrano[4',3':5,6]naphth[2,1-c]oxepin-3,10,12(1H,4H,10aH)-trione, 5-(acetyloxy)-8-(3-furanyl)decahydro-1,1,5a,7a,11b-pentamethyl-, (5S,5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)-

(5S,5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate

(5S,5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)-8-(3-Furyl)-1,1,5a,7a,11b-pentamethyl-3,10,12-trioxohexadecahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepin-5-yl acetate

1-(3-Furyl)decahydro-11-hydroxy-4b,7,7,11a,13a-pentamethyloxireno(4,4a)-2-benzopyrano[6,5-g](2)benzoxepin-3,5,9(3aH,4bH,6H)-trione Acetate