Ganodermanontriol

Modify Date: 2024-01-02 11:56:31

Ganodermanontriol structure	Common Name	Ganodermanontriol
	CAS Number	106518-63-2	Molecular Weight	472.700
	Density	1.1±0.1 g/cm3	Boiling Point	623.2±55.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₄₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	344.7±28.0 °C

Use of Ganodermanontriol

Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity[1][2].

Name	(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R,5S)-5,6,7-trihydroxy-6-methylheptan-2-yl]-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
Synonym	More Synonyms

Description	Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Ganodermanontriol inhibits breast cancer cell lines MCF-7 and MDA-MB-231with IC50 values of 5.8 and 9.7 μM, respectively[2].
References	[1]. Ha do T, et al. In vitro and in vivo hepatoprotective effect of ganodermanontriol against t-BHP-induced oxidative stress. Ethnopharmacol. 2013 Dec 12;150(3):875-85. [2]. Kennedy EM, et al. Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols. J Nat Prod. 2011 Nov 28;74(11):2332-7.

Density	1.1±0.1 g/cm3
Boiling Point	623.2±55.0 °C at 760 mmHg
Molecular Formula	C₃₀H₄₈O₄
Molecular Weight	472.700
Flash Point	344.7±28.0 °C
Exact Mass	472.355255
PSA	77.76000
LogP	5.66
Vapour Pressure	0.0±4.1 mmHg at 25°C
Index of Refraction	1.559