Florfenicol amine hydrochloride

Modify Date: 2024-01-13 17:47:07

Florfenicol amine hydrochloride Structure
Florfenicol amine hydrochloride structure
Common Name Florfenicol amine hydrochloride
CAS Number 108656-33-3 Molecular Weight 283.75
Density N/A Boiling Point N/A
Molecular Formula C10H15ClFNO3S Melting Point 162-164ºC
MSDS N/A Flash Point N/A

 Use of Florfenicol amine hydrochloride


Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases[1][2].

 Names

Name florfenicol amine, hydrochloride
Synonym More Synonyms

 Florfenicol amine hydrochloride Biological Activity

Description Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases[1][2].
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References

[1]. B-K Park, et al. Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus). J Vet Pharmacol Ther. 2006 Feb;29(1):37-40.  

[2]. Anadón A, et al. Plasma and tissue depletion of florfenicol and florfenicol-amine in chickens. J Agric Food Chem. 2008 Nov 26;56(22):11049-56.  

 Chemical & Physical Properties

Melting Point 162-164ºC
Molecular Formula C10H15ClFNO3S
Molecular Weight 283.75
Exact Mass 283.04500
PSA 88.77000
LogP 3.00340

 Synonyms

Florfenicol Amine Hydrochloride
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