Pyridin-3-ol

Modify Date: 2024-01-02 18:17:14

Pyridin-3-ol Structure
Pyridin-3-ol structure
Common Name Pyridin-3-ol
CAS Number 109-00-2 Molecular Weight 95.099
Density 1.2±0.1 g/cm3 Boiling Point 318.9±0.0 °C at 760 mmHg
Molecular Formula C5H5NO Melting Point 125-128 °C(lit.)
MSDS Chinese USA Flash Point 146.6±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Pyridin-3-ol


3-Hydroxypyridine is isolated from Bamboo grass. 3-Hydroxypyridine derivatives are structural analogues of vitamin B6 and have a wide range of pharmacological properties, such as antioxidant properties[1][2].

 Names

Name 3-Hydroxypyridine
Synonym More Synonyms

 Pyridin-3-ol Biological Activity

Description 3-Hydroxypyridine is isolated from Bamboo grass. 3-Hydroxypyridine derivatives are structural analogues of vitamin B6 and have a wide range of pharmacological properties, such as antioxidant properties[1][2].
Related Catalog
References

[1]. Atsushi Endo, et al. Bamboo grass extract and use of the same extract. JP2006298766A

[2]. L D Lukyanova, et al. Energotropic effect of succinate-containing derivatives of 3-hydroxypyridine. Bull Exp Biol Med. 2009 Oct;148(4):587-91.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 318.9±0.0 °C at 760 mmHg
Melting Point 125-128 °C(lit.)
Molecular Formula C5H5NO
Molecular Weight 95.099
Flash Point 146.6±20.4 °C
Exact Mass 95.037117
PSA 33.12000
LogP 0.64
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.560
Storage condition Store at RT.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU7701400
CHEMICAL NAME :
3-Pyridinol
CAS REGISTRY NUMBER :
109-00-2
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H5-N-O
MOLECULAR WEIGHT :
95.11
WISWESSER LINE NOTATION :
T6NJ CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1822 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,259,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UV1144050
HS Code 29333999

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

β-Hydroxypyridine
m-Hydroxypyridine
2-PYRIDON
3-Pyridinol
3-PYRIDOL
EINECS 205-520-3
T6NJ CQ
3-Pyridinol,3-Pyridone
3-HP
3-pyridinylphenol
pyridin-3-ol
B-PYRIDONE
3-Pyridyl alcohol
3-Oxopyridine
3-OH-pyridine
3-hydroxy-pyridine
3-PYRIDONE
MFCD00006268
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