Caffeoyltryptophan

Modify Date: 2024-09-02 15:03:12

Caffeoyltryptophan structure	Common Name	Caffeoyltryptophan
	CAS Number	109163-69-1	Molecular Weight	366.367
	Density	1.5±0.1 g/cm3	Boiling Point	771.3±60.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₁₈N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	420.3±32.9 °C

Use of Caffeoyltryptophan

Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC50 of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase, linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes[1].

Name	N-Caffeoyltryptophan
Synonym	More Synonyms

Description	Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC50 of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase, linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Metabolic Disease
References	[1]. Ha MT, et, al. PTP1B and α-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation. Phytochemistry. 2022 May:197:113100. [2]. Ohnishi M, et, al. Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. Phytochemistry. 1998 Apr;47(7):1215-8.

Description

Related Catalog

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

Research Areas >> Metabolic Disease

References

[1]. Ha MT, et, al. PTP1B and α-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation. Phytochemistry. 2022 May:197:113100.

[2]. Ohnishi M, et, al. Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. Phytochemistry. 1998 Apr;47(7):1215-8.

Density	1.5±0.1 g/cm3
Boiling Point	771.3±60.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₈N₂O₅
Molecular Weight	366.367
Flash Point	420.3±32.9 °C
Exact Mass	366.121582
LogP	2.11
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.745