Boc-DADdec

Modify Date: 2024-01-09 18:33:56

Boc-DADdec Structure
Boc-DADdec structure
Common Name Boc-DADdec
CAS Number 109792-60-1 Molecular Weight 300.48000
Density 0.924g/cm3 Boiling Point 409.2ºC at 760mmHg
Molecular Formula C17H36N2O2 Melting Point N/A
MSDS Chinese USA Flash Point 201.3ºC

 Use of Boc-DADdec


Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-boc-1,12-diaminododecane
Synonym More Synonyms

 Boc-DADdec Biological Activity

Description Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 0.924g/cm3
Boiling Point 409.2ºC at 760mmHg
Molecular Formula C17H36N2O2
Molecular Weight 300.48000
Flash Point 201.3ºC
Exact Mass 300.27800
PSA 64.35000
LogP 5.46200
Vapour Pressure 6.61E-07mmHg at 25°C
Index of Refraction 1.463

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
RIDADR NONH for all modes of transport
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Boc-DADdec
TERT-BUTYL 12-AMINODODECYLCARBAMATE
N-Boc-1,12-dodecanediamine
N-t-Butyloxycarbonyl-1,12-diaminododecane
N-tert-butoxycarbonyl-1,12-diaminododecane
1,12-Diaminododecane,N-BOC protected
tert-butyl 2,13-diaMinotridecanoate
mono-tert-butoxycarbonyl-1,12-diaminododecane