CI-966

Modify Date: 2024-01-08 17:38:43

CI-966 structure	Common Name	CI-966
	CAS Number	110283-79-9	Molecular Weight	473.40800
	Density	1.34g/cm3	Boiling Point	514.1ºC at 760mmHg
	Molecular Formula	C₂₃H₂₁F₆NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	264.7ºC

Use of CI-966

CI-966 (PD 126141) is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively.

Name	1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid
Synonym	More Synonyms

Density	1.34g/cm3
Boiling Point	514.1ºC at 760mmHg
Molecular Formula	C₂₃H₂₁F₆NO₃
Molecular Weight	473.40800
Flash Point	264.7ºC
Exact Mass	473.14300
PSA	49.77000
LogP	5.48480
Vapour Pressure	2.16E-11mmHg at 25°C
Index of Refraction	1.517

1,2,5,6-tetrahydro-1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3-pyridinecarboxylic acid methyl ester structure

1,2,5,6-tetrahy...

CAS#:132284-15-2

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CI-966 Structure

CI-966

CAS#:110283-79-9

Literature: Pavia, Michael R.; Lobbestael, Sandra J.; Nugiel, David; Mayhugh, Daniel R.; Gregor, Vlad E.; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4238 - 4248

4-(Trifluoromethyl)benzaldehyde structure

4-(Trifluoromet...

CAS#:455-19-6

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CI-966 Structure

CI-966

CAS#:110283-79-9

Literature: Pavia, Michael R.; Lobbestael, Sandra J.; Nugiel, David; Mayhugh, Daniel R.; Gregor, Vlad E.; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4238 - 4248

4-Bromobenzotrifluoride structure

4-Bromobenzotri...

CAS#:402-43-7

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CI-966 Structure

CI-966

CAS#:110283-79-9

Literature: Pavia, Michael R.; Lobbestael, Sandra J.; Nugiel, David; Mayhugh, Daniel R.; Gregor, Vlad E.; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4238 - 4248

4,4'-BIS(TRIFLUOROMETHYL)BENZHYDROL structure

4,4'-BIS(TRIFLU...

CAS#:22543-52-8

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CI-966 Structure

CI-966

CAS#:110283-79-9

Literature: Pavia, Michael R.; Lobbestael, Sandra J.; Nugiel, David; Mayhugh, Daniel R.; Gregor, Vlad E.; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4238 - 4248

Precursor 4
CAS#:132284-15-2 1,2,5,6-tetrahy... CAS#:455-19-6 4-(Trifluoromet... CAS#:402-43-7 4-Bromobenzotri... CAS#:22543-52-8 4,4'-BIS(TRIFLU...
DownStream 0

1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydro-3-pyridine carboxylic acid

1-(2-(Bis(4-(trifluoromethyl)phenyl)methoxy)ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid

CI-966

1,2,5,6-tetrahydro-1-<2-<bis<4-(trifluoromethyl)phenyl>methoxy>ethyl>-3-pyridinecarboxylic acid

3-Pyridinecarboxylicacid,1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydro

Tocris-1296

DC Chemicals Limited
China
Product Name: CI-966
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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